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Clinical Trials in the EU / 2025-520730-28-00
Completed Phase II

A Phase 2b, Open-Label, Two-cohort Study of Subcutaneous Amivantamab in Combination with Lazertinib as First-Line Treatment, or Subcutaneous Amivantamab in Combination with Platinum-Based Chemotherapy as Second-line Treatment, for Common EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer

2025-520730-28-00 · tracked via the Priya Life Science EU tracker
Sponsor
Janssen Cilag International
Sponsor type
Pharmaceutical company
Therapeutic area
Neoplasms
Decision date
27/11/2025
Enrollment target
118
Sites
Germany, Spain, Finland, Greece, Portugal, Italy, Belgium, Poland, France

Condition studied

Common EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Investigational medicinal product(s)

JNJ-73841937JNJ-61186372

Eligibility

Age group
18-64 years, 65+ years
Sex
Female, Male

Primary endpoint

PFS according to RECIST v1.1 by investigator assessment

Official registry record

This page summarises publicly available CTIS data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View 2025-520730-28-00 on CTIS ↗ ← All trials in the EU