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Clinical Trials in the EU / 2025-520610-58-00
Terminated Phase III

A Phase 3, Randomized, Active-Controlled, Double-Blind Clinical Study to Evaluate the Efficacy and Safety of MK-8527 Oral Once-Monthly as HIV-1 Preexposure Prophylaxis

2025-520610-58-00 · tracked via the Priya Life Science EU tracker
Sponsor
Merck Sharp & Dohme LLC
Sponsor type
Pharmaceutical company
Therapeutic area
Virus Diseases
Decision date
03/10/2025
Enrollment target
100
Sites
France

Condition studied

HIV-1 prevention

Investigational medicinal product(s)

Placebo for Emtricitabine/Tenofovir DisoproxilPlacebo for MK-8527TENOFOVIR DISOPROXIL AND EMTRICITABINEMK-8527 F1

Eligibility

Age group
18-64 years, 65+ years, 0-17 years
Sex
Female, Male

Primary endpoint

Number of Participants With Adjudicated Human Immunodeficiency Virus Type 1(HIV-1) Infection, Number of Participants Who Experience At Least One Adverse Event (AE), Number of Participants Who Discontinue Study Intervention Due to an AE

Official registry record

This page summarises publicly available CTIS data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View 2025-520610-58-00 on CTIS ↗ ← All trials in the EU