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Clinical Trials in the EU / 2024-516909-23-00
Completed Phase II

A Master Protocol for an Open-Label, Multi-Drug, Multi-Center, Phase II Platform Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Anti-Tumor Activity of Novel Agents or Combinations as Perioperative Treatment in Participants with Locally Advanced Resectable Gastroesophageal Adenocarcinoma (GEMINI-PeriOp GC)

2024-516909-23-00 · tracked via the Priya Life Science EU tracker
Sponsor
AstraZeneca AB
Sponsor type
Pharmaceutical company
Therapeutic area
Neoplasms
Decision date
01/09/2025
Enrollment target
34
Sites
Italy, Spain

Condition studied

Locally Advanced Resectable Gastroesophageal Adenocarcinoma

Investigational medicinal product(s)

AZD0901RilvegostomigDS-8201a

Eligibility

Age group
65+ years, 18-64 years
Sex
Female, Male

Primary endpoint

-The measures of interest include the incidence of AEs and SAEs, and descriptive statistics summarizing laboratory findings, vital signs, and ECGs., -The analysis will include participants in mITT. -The measure of interest is the pCR rate, which is the proportion of participants with 0% residual viable tumor cells within all resected tissue.

Official registry record

This page summarises publicly available CTIS data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View 2024-516909-23-00 on CTIS ↗ ← All trials in the EU