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Clinical Trials in the EU / 2022-501458-13-01
Completed Phase II

Pembro-FLASH - Phase II trial of Pembrolizumab in First-Line Treatment of Advanced-Stage Classic Hodgkin Lymphoma

2022-501458-13-01 · tracked via the Priya Life Science EU tracker
Sponsor
University Of Cologne
Sponsor type
Educational Institution
Therapeutic area
Neoplasms
Decision date
30/09/2025
Enrollment target
40
Sites
Germany

Condition studied

Advanced Stage of Classic Hodgkin Lymphoma

Investigational medicinal product(s)

CYCLOPHOSPHAMIDEDOXORUBICINDACARBAZINE CITRATEETOPOSIDEADCETRIS 50 mg powder for concentrate for solution for infusion.DEXAMETHASONEKEYTRUDA 25 mg/mL concentrate for solution for infusion

Eligibility

Age group
18-64 years
Sex
Female, Male

Primary endpoint

1-year PFS estimate

Endpoint detail

Adverse events, Target number of P-BrECADD cycles per 100 participants, Remission status after 1x P (PET-1), 1x P + 2x P-BrECADD (PET-3) and after completion of PET-guided chemo-immunotherapy (PET-5 or PET-7, respectively), Overall survival after one year, Patient-reported outcomes (PRO-CTCAE, Fatigue, QLQ-C30 and Quality of Life)

Official registry record

This page summarises publicly available CTIS data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View 2022-501458-13-01 on CTIS ↗ ← All trials in the EU