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Trackers› Clinical trials› Multiple sclerosis
Clinical trial register · European Union · CTIS

Multiple sclerosis Clinical Trials in the EU, 2026

The most recently authorised trials on the EU Clinical Trials Information System (CTIS), the single register for every trial run under the EU Clinical Trials Regulation (536/2014). CTIS holds a far larger historical archive than any one list can usefully show โ€” this register states both numbers rather than picking one.

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Source: EMA Clinical Trials Information System (CTIS). Showing the 2500 most recently authorised of 12490 total CTIS records โ€” a stated recency window, not the full historical archive. Synced 25 Sep 2026, 03:16 UTC
2500
Shown in this register
most recently authorised
12,490
Total on CTIS
full historical archive
741
Phase III
within the shown window
Top member states
Spain 1016 France 881 Germany 860 Italy 735 Poland 585 Netherlands 531
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Trials for Multiple sclerosis

12 of 2500 shown studies
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Phase
Study
Lead sponsor
Area
Member states
Decision
Phase I
A Randomised, Placeboโ€‘Controlled Trial to Assess Effect of IMUโ€‘838 on QT/QTc
2026-526859-54-00Multiple sclerosis
Immunic AG
Nervous System Diseases
Belgium
31/07/2026
Phase III
A Randomized Open Label Trial Exploring the Soluble and Imaging Biomarker Dynamic Responses to Tolebrutinib Compared to Rituximab Treatment in Patients with Multiple Sclerosis (MS)
2025-523892-50-00Multiple Sclerosis
Region Stockholm โ€“ SLSO
Nervous System Diseases
Sweden
02/06/2026
Phase IV
Effects of CLADribine tablets on the Immune Synapse, in Relapsing Multiple Sclerosis (RMS) patients_CLADIS.
2025-521910-24-00Multiple Sclerosis
Aristotle University Of Thessaloniki
Nervous System Diseases
Greece
17/04/2026
Phase III
A randomized, Phase 3, open-label study to investigate pharmacokinetics, safety, and efficacy of subcutaneous compared to intravenous frexalimab in adult participants with multiple sclerosis.
2024-519304-28-00Multiple Sclerosis
Sanofi-Aventis Recherche & Developpement
Nervous System Diseases
Belgium, Spain, Italy
08/04/2026
Phase I
A Phase 1, drug-drug interaction trial of IMU-838 with oral contraceptives in women
2026-525208-90-00Multiple sclerosis
Immunic AG
Nervous System Diseases
Belgium
16/03/2026
Phase II
PRObiotic Therapy Examining Combinatorial Therapeutics in Multiple Sclerosis - phase II, multicenter, randomised, open-label clinical trial.
2025-520955-10-00Multiple sclerosis
Wojskowy Instytut Medyczny Panstwowy Instytut Badawczy
Nervous System Diseases
Poland
20/10/2025
Rows per page Showing 1–12 of 12
1
Cite this view

Priya Life Science (2026). EU Clinical Trials Register (CTIS), filtered. Derived from the EMA Clinical Trials Information System. Retrieved 25 September 2026. https://priyalifescience.com/clinical-trials-europe/condition/multiple-sclerosis

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About this register

This register is built from the EU Clinical Trials Information System (CTIS), run by the European Medicines Agency: the single register for every trial authorised under the EU Clinical Trials Regulation (536/2014). CTIS held 12,490 trial records at the last sync on 25 Sep 2026, 03:16 UTC; this register shows the 2,500 most recently authorised of them, a stated recency window rather than the full archive. The list can be downloaded as CSV or JSON.

This page shows the 12 of those trials with a site in Multiple sclerosis.

How many recently authorised EU trials have a site in Multiple sclerosis?

12 of the 2,500 most recently authorised trials in this register list a site in Multiple sclerosis; 3 of them are Phase III. Trials are counted by authorisation on CTIS, not by recruitment status, which CTIS does not publish in the same form as ClinicalTrials.gov.

Summary by phase

Trials by phase (Multiple sclerosis), 12 trials
PhaseTrialsShare
Phase II541.7%
Phase I325%
Phase III325%
Phase IV18.3%

Most active sponsors

Lead sponsors with the most trials (Multiple sclerosis)
Lead sponsorTrials
Immunic AG3
Amsterdam UMC Stichting1
Aristotle University Of Thessaloniki1
F. Hoffmann-La Roche AG1
Region Stockholm โ€“ SLSO1
Sanofi-Aventis Recherche & Developpement1
Tg Therapeutics Inc.1
Universitair Ziekenhuis Antwerpen, Hospital Germans Trias I Pujol1
Varsinais-Suomen hyvinvointialue1
Wojskowy Instytut Medyczny Panstwowy Instytut Badawczy1
Listing here is informational and not medical advice; eligibility is determined by each study team. Looking for Irish sites? See the Ireland, UK or USA registers. For approved medicines, see the EMA Approvals Tracker.