Tooth LossPartial Edentulism in the Maxilla or in the Mandible
Investigational drug(s) / intervention(s)
Immediate implant with autogenous bone graftImmediate implant without bone graft
Immediate implant with autogenous bone graft: Immediate implant with autogenous bone graft using piezo surgery
Immediate implant without bone graft: Immediate implant without bone graft
Study summary
This clinical study aims to evaluate the clinical and radiographic outcomes of immediate dental implant placement in mandibular premolar sites. Patients requiring extraction of mandibular premolars will receive immediate implant placement, with or without autogenous bone grafting, according to the study protocol.
When indicated, autogenous bone graft will be harvested using piezosurgery during the implant procedure. Participants will be followed up clinically and radiographically to assess implant stability, marginal bone level changes, and peri-implant tissue conditions over a defined follow-up period. The results of this study may help determine the effectiveness and predictability of immediate implant placement in mandibular premolar regions.
Eligibility
Sex
ALL
Min age
25 Years
Max age
45 Years
Healthy volunteers
Accepted
Inclusion Criteria:
* Patients requiring extraction of mandibular premolars.
* Age ≥ 25 years.
* Adequate oral hygiene and motivated patients for implant treatment.
* Sufficient bone volume to allow immediate implant placement (with or without minor augmentation).
* Patients willing to participate and attend follow-up visits for at least 6 months.
* Systemically healthy patients (ASA I or II).
Exclusion Criteria:
* Uncontrolled systemic diseases (e.g., uncontrolled diabetes, immunocompromised patients).
* Heavy smokers (e.g., \>10-15 cigarettes/day).
* Active periodontal or acute infection at the implant site.
* Poor oral hygiene or non-compliant patients.
* Pregnancy or lactation.
* History of radiotherapy in head and neck region.
* Severe bone deficiency not suitable for immediate implant placement.
Primary outcome measure(s)
Osseointegration success rate (%) — 6 months after implant placement. Implant success will be evaluated based on the absence of mobility, pain, infection, and peri-implant radiolucency around the implant.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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