Pharmacological treatment: All participants in the two groups will receive pharmacological treatment in the form of ibuprofen 400 mg, three times per day, during the first 2 days of menstruation, for 3 menstrual cycles.
Virtual reality: The experimental group will receive virtual reality during the first 2 days of menstruation, for 3 menstrual cycles.
Study summary
This study will be conducted to study the effect of virtual reality therapy on prostaglandin levels in adolescent females with primary dysmenorrhea.
Eligibility
Sex
FEMALE
Min age
17 Years
Max age
21 Years
Healthy volunteers
No
Inclusion Criteria:
* Age 17- 21 years old.
* The body mass index (BMI) \< 30 kg/m2.
* Unmarried females.
* Females with dysmenorrhea pain.
* Females with regular menstrual cycles.
* Females with normal gynecology.
Exclusion Criteria:
* Have a pathological disease related to reproduction.
* Students who use analgesic drugs for 3 months/3 menstrual cycles.
* Students with menstrual pain secondary to diagnosed organic or inflammatory causes.
Primary outcome measure(s)
Visual Analogue Scale (VAS) — 12 weeks Participants in both groups will complete the visual analogue scale (VAS) before the start of treatment and after 3 menstrual cycles of treatment. The VAS is a 10 cm horizontal line on which the participants' pain intensity is represented by a point between the extremes of "no pain at all "and "worst pain imaginable". Each girl will be asked to mark a point on the line between the extreme that was related to her pain intensity. Then, the distance will be measured each time from the left end of the line to the marked point to obtain the VAS score for pain intensity of dysmenorrhea.
Assessment of Prostaglandin Levels — 12 weeks Blood samples will be collected from each girl in both groups to measure the levels of plasma PGF2α before the start of treatment and after 3 menstrual cycles of treatment.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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