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Clinical Trials in Egypt / NCT06973135
Active, not recruiting Not applicable

Non-Surgical Single Visit Endodontic Retreatment in Cases With Asymptomatic Apical Periodontitis Using Bioceramic Sealer

NCT06973135 · tracked via the Priya Life Science Egypt tracker
Sponsor
Saly Nazeer
Phase
Not applicable
Started
2025-06-01
Last updated
2026-08-06

Condition(s) studied

Asymptomatic Apical PeriodontitisRoot Canal Retreatment

Investigational drug(s) / intervention(s)

Bioceramic sealer root canal obturationresin sealer root canal obturation

Bioceramic sealer root canal obturation: Mandibular molars root canal obturation with bioceramic sealer after non surgical endodontic retreatment and then immediate periapical radiograph will be done to record PAI

resin sealer root canal obturation: non surgical root canal retreatment of mandibular molar teeth will be done using resin based sealer in obturation and periapical radiograph will be taken immediately to record PAI

Study summary

The goal of this clinical trial is to learn if using bioceramic sealers in non surgical single visit endodontic retreatment in patients with endodontic treatment failure and asymptomatic apical periodontitis will work in comparison to other resin sealer which proved efficacy ,and help healing of the periapical lesions and reduce the anticipated postoperative pain , Participants will have root canal retreatment done in a single visit and then follow up will be done in 1, 3 and 6 months to check healing and then after 12 months , also postoperative pain will be monitored through communicating the patients after 24, 28 , 72 hours and the 7 days

Eligibility

Sex
ALL
Min age
18 Years
Max age
65 Years
Healthy volunteers
No
Inclusion Criteria: 1. Mandibular molar teeth with previous unsuccessful endodontic treatment from ≥ 1 year with asymptomatic apical periodontitis. 2. Teeth with inadequate obturation. 3. Teeth with broken instruments that can be bypassed and/or retrieved and not present in the apical third or passing through the apex. 4. Teeth with periapical lesion. 5. Patient with the ages of 18-65 years. 6. Patient medically healthy and free from systemic diseases or with mild controlled systemic disease. ASA I, II \* (52). 7. Patient with no acute pain or extraoral swelling. 8. Patients who agreed to participate in the study and attend the control visits. \- Exclusion Criteria: 1. Teeth requiring retreatment with a poor prognosis (root canal morphology altered, large carious cavity, internal or external root resorption, root perforation) 2. Teeth with vertical root fracture or open apex. 3. Patient with systemic disorders related to bone metabolism and using drugs that may affect bone metabolism. 4. Pregnant patients. 5. Patient under antibiotics treatment 2 weeks before the treatment. 6. Patients who could not attend follow up will be excluded from the study \-

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
faculty of dentistry Alexandria university Alexandria Alexandria Governorate

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06973135 on ClinicalTrials.gov ↗ ← All trials in Egypt