frusemide: in this group we use vexus score to asses decongestion in comparison to lung ultrasound in other group
Study summary
the goal of this observational study is to evaluate the role of VEXUS score and lung ultrasound to guide decongestive therapy in patients with cardiorenal syndrome type -1. the main question it aims to answer is: Can the VEXUS score and lung ultrasound guide the efffect of decongestive therapy on KFR and decongestion metrics in patients with CRS-1 compared to standard assesment ?
Eligibility
Sex
ALL
Min age
18 Years
Max age
65 Years
Healthy volunteers
Accepted
Inclusion Criteria:
* • Patients of both genders aged 18-65 years old.
* Patients with CRS1 criteria (worsening of renal function due to acute heart failure manifested by : ( Dyspnea , orthopnea ,hypoxia , congested neck veins , oliguria and congestion in imaging.)
* Patients with Modified lung ultrasound score(LUSS) more than 15.
Exclusion Criteria:
* • Refusal to participate.
* Patients with renal transplantation.
* Unknowing baseline creatinine.
* Patients with a life-threatening indication of RRT (defined as intractable hyperkalemia, acidosis, uremic symptoms) at enrollment,
* RRT before recruitment,
* known prehospitalization advanced chronic kidney disease (defined by an estimated GFR \<30 mL/min/1.73 m2 or chronic RRT),
* use of extracorporeal membrane oxygenation (ECMO),
* diagnosis of hepatic cirrhosis or other condition with portal hypertension
* Or postrenal causes of AKI
Primary outcome measure(s)
assesment of KFR using the KDIGO AKI staging improvement — 1 week stage1:serum creatinine increase 1,5 - 2 folds serum creatinine increase 2 - 3 folds serum creatinine increase more than 3 folds
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
We use cookies to analyse site traffic and improve your experience. With your consent, we may also use cookies for advertising. You can change your choice at any time.