Medical Large Language Model-Assisted Diagnosis and Treatment in Primary Care Chronic Disease Management

Condition(s) studied

Investigational drug(s) / intervention(s)

Medical large language model: The primary care physicians in the intervention group completed the management decisions for chronic disease cases, including disease assessment, examination suggestions, treatment plans, selection of management methods, and health education, with the assistance of the medical LLM.

Study summary

This study aims to explore the feasibility of using medical large language models to assist in chronic disease management. By setting up experimental and control group interventions and having experts blindly evaluate anonymized cases, it compares different management approaches in chronic disease care, verifying the scientific basis, effectiveness, and potential for broader use of medical large language models in supporting chronic disease management.

Eligibility

Primary outcome measure(s)

• expert overall scores — through study completion, an average of 3 months.
  A total of 200 cases (50 each of coronary heart disease, atrial fibrillation, heart failure, and stroke) were grouped by disease type and independently evaluated in a blinded manner by three subspecialty experts. For each case, the two management plans were anonymized in the same way and then randomly labeled by a computer as Plan A and Plan B. Experts could only view the anonymized case information and the two corresponding anonymized management plans. They rated them using a Likert scale on several aspects: accuracy of condition assessment, reasonableness of test recommendations, reasonableness of treatment plans, appropriateness of management choices, scientific nature of patient education content, feasibility at the primary care level, overall clinical quality. Experts were instructed to rank the seven dimensions from lowest to highest quality. These ordinal rankings were then converted into standardized scores of 1 to 5. Higher scores mean better.

Trial sites (1)

More Jiangsu Taizhou People's Hospital trials in China

Other trials for the same condition