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Effect of Hot Spring Therapy on Central Fatigue Elimination During Altitude Training
Condition(s) studied
Central FatigueAltitude TrainingCognitive ImpairmentHydrotherapyBalneotherapySports Performance
Investigational drug(s) / intervention(s)
Natural recoveryHot water immersionHot spring balneotherapy
Natural recovery: Standard post-exercise recovery without water immersion. Participants rest passively in a thermoneutral environment (24°C, 50-60% humidity) for 20 minutes with ad libitum water and optional self-directed stretching. No heat, cold, or hydrotherapy interventions are applied.
Hot water immersion: After exercise, full-body immersion in daily tap water. Temperature: 38°C ± 0.5°C. Duration: 20 minutes per session, 3 times per week (Tuesday, Thursday, Saturday at 16:00), for 4 consecutive weeks (total of 12 sessions). Protocol: Full-body immersion below the neck for 20 minutes, followed by a 10-minute rest before leaving the facility.
Hot spring balneotherapy: After exercise, full-body immersion in natural hot spring water (pH approx. 7.4, Na+ 1210 mg/L, HCO3- approx. 3300 mg/L, total dissolved solids \>1000 mg/L). Temperature: 38°C ± 0.5°C. Duration: 20 minutes per session, 3 times per week (Tuesday, Thursday, Saturday at 16:00), for 4 consecutive weeks (12 sessions total). Protocol: Full-body immersion below the neck for 20 minutes, followed by a 10-minute rest before leaving the facility.
Study summary
This randomized controlled trial investigates the effects of hot spring balneotherapy on central fatigue elimination in adolescent rowers undergoing altitude training at approximately 1600 meters (Tengchong, Yunnan). Thirty adolescent athletes (aged 12-16 years) will be stratified by sex and randomly allocated to three groups: Group A (natural recovery, no immersion), Group B (38°C pure water immersion), and Group C (38°C sodium bicarbonate hot spring immersion). Interventions will be administered 3 times per week for 4 weeks. The primary outcomes are central fatigue indices including voluntary activation (VA) and central activation ratio (CAR). Secondary outcomes encompass cognitive function (Stroop test, Psychomotor Vigilance Test), cerebral hemodynamics (functional near-infrared spectroscopy, transcranial Doppler ultrasound), exercise performance (maximal oxygen uptake, 1000m test, 500m test), blood lactate, and hematological parameters (white blood cells, neutrophils, platelets).
Eligibility
Inclusion Criteria:
* Male or female aged 12-16 years- Healthy with no serious chronic diseases or skin conditions
* At least 1 year of systematic rowing training experience
* Currently undergoing centralized altitude training at approximately 1600 meters- No history of systematic hot spring or spa immersion within the past month
* No allergy history to sodium bicarbonate or hot spring minerals- Ability to provide written informed assent (participant) and written informed consent (parent/guardian)- No acute infection, fracture, or surgery within the past month
* Not currently taking non-steroidal anti-inflammatory drugs (NSAIDs), immunosuppressants, or medications affecting autonomic or cognitive function
Exclusion Criteria:
* History of cardiovascular, respiratory, renal, endocrine, or neurological disorders- Uncontrolled hypertension or hypotension
* History of syncope, heat intolerance, or severe dizziness during hot water immersion- Open wounds, severe eczema, or other skin conditions contraindicating water immersion
* Current use of beta-blockers, anticholinergics, stimulants, sedatives, or other medications affecting central nervous system function
* Color blindness or uncorrected visual impairment affecting Stroop test performance- Pregnancy (for female participants)- Alcohol consumption or smoking
* Shift work or trans-meridian travel within 2 weeks prior to baseline assessment
* Any condition deemed by the investigator as unsafe for participation
Primary outcome measure(s)
- Voluntary Activation — Baseline (Week 0), Week 2, Week 3, Week 4 (post-intervention), Follow-up (Week 1-2 post-altitude)
Voluntary activation assessed by the interpolated twitch technique (ITT) during maximal voluntary contraction (MVC) of the quadriceps femoris using percutaneous electrical stimulation. A single stimulus is superimposed on MVC; VA is calculated as: VA = (1 - superimposed twitch force / potentiated resting doublet force) × 100%. Higher VA indicates greater central neural drive. Unit: percentage (%).
- Central Activation Ratio — Baseline (Week 0), Week 2, Week 3, Week 4, Follow-up (Week 5-6 post-altitude)
Central activation ratio measured as the ratio of maximal voluntary contraction force to the force evoked by supramaximal electrical stimulation of the femoral nerve during quadriceps contraction. CAR = MVC force / (MVC force + superimposed twitch force). Values closer to 1.0 indicate less central fatigue. Unit: ratio (0-1, no units).
Trial sites (1)
| Facility | City | Region | Status |
| Macao Polytechnic University |
Macao |
Macao |
Recruiting |
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