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Clinical Trials in China / NCT07615478
Recruiting Not applicable

Effect of Hot Spring Therapy on Central Fatigue Elimination During Altitude Training

NCT07615478 · tracked via the Priya Life Science China tracker
Sponsor
Macao Polytechnic University
Phase
Not applicable
Started
2026-05-25
Last updated
2026-05-29

Condition(s) studied

Central FatigueAltitude TrainingCognitive ImpairmentHydrotherapyBalneotherapySports Performance

Investigational drug(s) / intervention(s)

Natural recoveryHot water immersionHot spring balneotherapy

Natural recovery: Standard post-exercise recovery without water immersion. Participants rest passively in a thermoneutral environment (24°C, 50-60% humidity) for 20 minutes with ad libitum water and optional self-directed stretching. No heat, cold, or hydrotherapy interventions are applied.

Hot water immersion: After exercise, full-body immersion in daily tap water. Temperature: 38°C ± 0.5°C. Duration: 20 minutes per session, 3 times per week (Tuesday, Thursday, Saturday at 16:00), for 4 consecutive weeks (total of 12 sessions). Protocol: Full-body immersion below the neck for 20 minutes, followed by a 10-minute rest before leaving the facility.

Hot spring balneotherapy: After exercise, full-body immersion in natural hot spring water (pH approx. 7.4, Na+ 1210 mg/L, HCO3- approx. 3300 mg/L, total dissolved solids \>1000 mg/L). Temperature: 38°C ± 0.5°C. Duration: 20 minutes per session, 3 times per week (Tuesday, Thursday, Saturday at 16:00), for 4 consecutive weeks (12 sessions total). Protocol: Full-body immersion below the neck for 20 minutes, followed by a 10-minute rest before leaving the facility.

Study summary

This randomized controlled trial investigates the effects of hot spring balneotherapy on central fatigue elimination in adolescent rowers undergoing altitude training at approximately 1600 meters (Tengchong, Yunnan). Thirty adolescent athletes (aged 12-16 years) will be stratified by sex and randomly allocated to three groups: Group A (natural recovery, no immersion), Group B (38°C pure water immersion), and Group C (38°C sodium bicarbonate hot spring immersion). Interventions will be administered 3 times per week for 4 weeks. The primary outcomes are central fatigue indices including voluntary activation (VA) and central activation ratio (CAR). Secondary outcomes encompass cognitive function (Stroop test, Psychomotor Vigilance Test), cerebral hemodynamics (functional near-infrared spectroscopy, transcranial Doppler ultrasound), exercise performance (maximal oxygen uptake, 1000m test, 500m test), blood lactate, and hematological parameters (white blood cells, neutrophils, platelets).

Eligibility

Sex
ALL
Min age
12 Years
Max age
16 Years
Healthy volunteers
Accepted
Inclusion Criteria: * Male or female aged 12-16 years- Healthy with no serious chronic diseases or skin conditions * At least 1 year of systematic rowing training experience * Currently undergoing centralized altitude training at approximately 1600 meters- No history of systematic hot spring or spa immersion within the past month * No allergy history to sodium bicarbonate or hot spring minerals- Ability to provide written informed assent (participant) and written informed consent (parent/guardian)- No acute infection, fracture, or surgery within the past month * Not currently taking non-steroidal anti-inflammatory drugs (NSAIDs), immunosuppressants, or medications affecting autonomic or cognitive function Exclusion Criteria: * History of cardiovascular, respiratory, renal, endocrine, or neurological disorders- Uncontrolled hypertension or hypotension * History of syncope, heat intolerance, or severe dizziness during hot water immersion- Open wounds, severe eczema, or other skin conditions contraindicating water immersion * Current use of beta-blockers, anticholinergics, stimulants, sedatives, or other medications affecting central nervous system function * Color blindness or uncorrected visual impairment affecting Stroop test performance- Pregnancy (for female participants)- Alcohol consumption or smoking * Shift work or trans-meridian travel within 2 weeks prior to baseline assessment * Any condition deemed by the investigator as unsafe for participation

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Macao Polytechnic University Macao Macao Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07615478 on ClinicalTrials.gov ↗ ← All trials in China