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Clinical Trials in China / NCT07603102
Recruiting Not applicable

Mindfulness With Dual-Task Training in Post-Stroke Mild Cognitive Impairment

NCT07603102 · tracked via the Priya Life Science China tracker
Sponsor
Nanjing Mingzhou Rehabilitation Hospital
Phase
Not applicable
Started
2026-05-01
Last updated
2026-05-22

Condition(s) studied

StrokeMild Cognitive Impairment (MCI)

Investigational drug(s) / intervention(s)

mindfulnessDual-Task TrainingAerobic TrainingHealth education

mindfulness: Guided by a professional mindfulness instructor, participants engage in mindfulness meditation to enhance attention, emotional regulation, and cognitive readiness. The training includes breath awareness, body scan, and present-moment awareness, delivered through guided meditation.Other Name:

Dual-Task Training: Dual-task training is a rehabilitation approach that targets cognitive-motor integration by requiring participants to perform a motor task and a cognitive task simultaneously. Examples include walking while performing mental calculations, memory tasks, or reaction-based exercises. The training is progressively adjusted by increasing task difficulty and cognitive load to improve attention allocation, executive function, and dual-task performance in daily activities.

Aerobic Training: Dual-task training is a rehabilitation approach that targets cognitive-motor integration by requiring participants to perform a motor task and a cognitive task simultaneously. Examples include walking while performing mental calculations, memory tasks, or reaction-based exercises. The training is progressively adjusted by increasing task difficulty and cognitive load to improve attention allocation, executive function, and dual-task performance in daily activities.

Health education: Health education is a non-exercise control intervention designed to provide participants with knowledge related to post-stroke health management. Topics include stroke recovery, healthy lifestyle behaviors, nutrition, medication adherence, daily activity management, and psychological well-being. The intervention is delivered through structured educational sessions or instructional materials and does not include active physical or cognitive training components.

Study summary

This study aims to investigate whether a combined intervention of mindfulness and dual-task training can improve cognitive function and physical performance in individuals with mild cognitive impairment after stroke.

Eligibility

Sex
ALL
Min age
55 Years
Max age
Healthy volunteers
No
Inclusion Criteria: * Diagnosis of stroke confirmed by computed tomography (CT) or magnetic resonance imaging (MRI). * Time since stroke onset ≥3 months and medically stable. * Presence of mild cognitive impairment after stroke, defined by a Montreal - - Montreal Cognitive Assessment (MoCA) score \< 26. * Mini-Mental State Examination (MMSE) score ≥ 24. * Ability to walk independently with or without an assistive device for at least 10 meters. * Stable medication regimen for at least 4 weeks prior to enrollment. * Ability to understand study instructions and provide written informed consent. Exclusion Criteria: * Severe aphasia, visual impairment, hearing impairment, or communication disorders that interfere with assessment or training participation. * Severe depression or other major psychiatric disorders. * Other neurological diseases affecting cognition or movement (e.g., Parkinson's disease, multiple sclerosis, traumatic brain injury). * Severe musculoskeletal, cardiovascular, or systemic diseases that contraindicate exercise participation. * Participation in other structured cognitive or rehabilitation intervention programs within the past 3 months. * Unstable medical condition or recurrent stroke during the study period. * Inability to safely complete the training protocol as determined by the study investigators.

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Nanjing Mingzhou Rehabilitation Hospital Nanjing China Recruiting

More Nanjing Mingzhou Rehabilitation Hospital trials in China

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07603102 on ClinicalTrials.gov ↗ ← All trials in China