A Multi-Center Randomized Controlled Trial on the Impact of Disease Subtype-Based Active Video Education on Bowel Preparation Quality in Patients With Inflammatory Bowel Disease

NCT07582731 · tracked via the Priya Life Science China tracker

Sponsor

Jie Liang

Phase

Not applicable

Started

2026-06-01

Last updated

2026-06-16

Condition(s) studied

Inflammatory Bowel Diseases

Investigational drug(s) / intervention(s)

Disease Subtype-Based Active Video Educationstandard bowel preparation education

Disease Subtype-Based Active Video Education: A structured, subtype-specific educational video program tailored for patients with inflammatory bowel disease (IBD). The videos are customized based on IBD subtype (ulcerative colitis/Crohn's disease), disease activity (active/remission), and Crohn's disease behavior (stricturing/fistulizing). It covers key topics including dietary restrictions, laxative intake instructions, symptom management, and practical problem-solving strategies to improve understanding and adherence to bowel preparation protocols. The video is delivered via WeChat link.

standard bowel preparation education: standard bowel preparation education

Study summary

This multi-center, prospective, randomized controlled trial evaluates whether disease subtype-based active video education improves bowel preparation quality in patients with inflammatory bowel disease (IBD) undergoing colonoscopy. A total of 600 IBD patients from 13 centers will be randomized 1:1 to standard education plus subtype-specific video education (intervention group) or standard education alone (control group). The primary outcome is the Boston Bowel Preparation Scale (BBPS) score.

Eligibility

Sex

ALL

Min age

18 Years

Max age

75 Years

Healthy volunteers

Inclusion Criteria: 1. Age between 18 and 75 years, inclusive. 2. Confirmed diagnosis of Ulcerative Colitis (UC) or Crohn's disease (CD) according to standard clinical guidelines. 3. Scheduled for elective colonoscopy for IBD monitoring or disease activity assessment. 4. Able to understand written and verbal instructions and to use a smartphone to view video education materials. 5. Voluntary participation with written informed consent. Exclusion Criteria: 1. Absolute contraindications to colonoscopy, including acute gastrointestinal perforation, fulminant colitis, toxic megacolon, or hemodynamic instability. 2. History of total or subtotal colectomy. 3. Acute or chronic intestinal obstruction. 4. Severe cardiac, pulmonary, hepatic, or renal insufficiency (eGFR \<30 mL/min/1.73m², NYHA class III/IV). 5. Severe psychiatric or cognitive impairment that prevents understanding of the study requirements. 6. Inability or unwillingness to provide written informed consent. 7. Pregnant or breastfeeding women.

Primary outcome measure(s)

Bowel Preparation Quality (Boston Bowel Preparation Scale, BBPS) — Periprocedural (during colonoscopy)
The Boston Bowel Preparation Scale (BBPS) is a validated scoring system to assess the cleanliness of three colonic segments: right colon (including cecum and ascending colon), transverse colon (including hepatic flexure and splenic flexure), and left colon (including descending colon, sigmoid colon, and rectum). Each segment is scored from 0 (unprepared) to 3 (excellent) by the endoscopist during withdrawal. The total BBPS score ranges from 0 to 9. Higher scores indicate better bowel preparation.

Trial sites (12)

Facility	City	Region
Peking Union Medical College Hospital	Beijing	BeijingBeijing
Shengjing Hospital of China Medical University	Shenyang	Liaoning
Affiliated Hospital of Qinghai University	Xining	Qinghai
The Second Affiliated Hospital of Xi'an Jiaotong University	Xi'an	Shaanxi
Air Force 986 Hospital	Xi'an	Shaanxi
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine	Shanghai	Shanghai Municipality
Renji Hospital, Shanghai Jiao Tong University School of Medicine	Shanghai	Shanghai Municipality
Changhai Hospital, Naval Medical University	Shanghai	Shanghai Municipality
Heping Hospital affiliated to Changzhi Medical College	Changzhi	Shanxi
Linfen Central Hospital	Linfen	Shanxi
Yuncheng Central Hospital	Yuncheng	Shanxi
The First Affiliated Hospital of Xinjiang Medical University	Ürümqi	Xinjiang

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07582731 on ClinicalTrials.gov ↗ ← All trials in China