there is no intervention in this study: there is no intervention
Study summary
For patients with severe calcification or complex non-calcified plaques, we investigate wether PCCT can enable non-invasive, in vivo precise differentiation and quantitative measurement of plaque components (e.g., spotty calcification, necrotic core, fibrous tissue). Further we also study wether these quantitative imaging features can independently predict the risk of MACE in the short term and long term
Eligibility
Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criter:
* Adult patients (≥18 years) with clinically diagnosed coronary artery disease or undergoing CCTA for chest pain/heart failure symptoms.
* Able and willing to provide informed consent and complete scheduled follow-up visits.
Exclusion Criteria:
* History of iodine contrast agent allergy.
* Severe renal insufficiency (eGFR \< 30 mL/min/1.73 m²).
* History of prior coronary artery bypass grafting (CABG).
* Pregnant or lactating women
Primary outcome measure(s)
Major Adverse Cardiovascular Events, MACE — 12months Non-fatal myocardial infarction Non-fatal stroke Cardiovascular death Revascularization Acute heart failure
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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