Multi-source data-integrated HIV cohort in four cities of southern Sichuan, China: a mixed retrospective-prospective study protocol.
Eligibility
Sex
ALL
Min age
18 Years
Max age
85 Years
Healthy volunteers
No
Inclusion Criteria:
* People living with HIV (PLWH) or AIDS patients who are registered and diagnosed at the participating research centers in Luzhou, Zigong, Neijiang, or Yibin, China
* Key assessment information (clinical, laboratory, or follow-up data) obtainable during the study period
* Traceable medical treatment or follow-up records within the retrospective time window (1 January 2019 to 31 December 2025)
* Able to understand and complete the questionnaire and provide written informed consent (for the prospective component)
* Residing or visiting within the four southern Sichuan cities, or continuously managed at the local research centers
Exclusion Criteria:
* Missing key information that cannot be verified or supplemented from original records
* Unable to complete the questionnaire and no alternative data collection method available
* Obviously inconsistent or untrustworthy data that cannot be confirmed after verification
* Not suitable for inclusion under ethical and compliance requirements (e.g., unable to provide consent without a legally authorized representative when required)
Primary outcome measure(s)
12-month virological suppression — 12 months (±60 days) after baseline Proportion of participants achieving HIV RNA \<50 copies/mL measured at the 12-month assessment window (±60 days). This binary outcome is derived from routinely collected viral load measurements extracted from CDC registries or hospital electronic medical records. If multiple measurements exist within the window, the value closest to the 12-month target date is used. This definition aligns with UNAIDS 95-95-95 targets and Chinese national treatment guidelines.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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