Mecapegfilgrastim Injection: Use it 24 hours after the end of each treatment cycle at a fixed dose of 6 mg or 100μg/kg each time
Study summary
This study is a multicenter, observational real-world study, aiming to observe and evaluate the efficacy and safety of prophylactic application of Mecapegfilgrastim Injection in tumor patients after radiotherapy/chemotherapy/immunotherapy in the real world to prevent neutropenia.The subjects who met the inclusion criteria of the protocol were defined as those who needed radiotherapy/chemotherapy/immunotherapy after being diagnosed with solid malignant tumors. The researchers believed that the subjects needed to use Mecapegfilgrastim Injection for primary/secondary prevention after receiving tumor treatment.
Eligibility
Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria:
* 1\. Patients with malignant tumors confirmed by histopathology or cytology; 2. Age ≥18 years old; 3. After referring to various guidelines, the researchers believed that the subjects:
1. Patients who are currently receiving treatment regimens with high FN risk;
2. Patients who are currently receiving treatment regimens for moderate FN risk and meet any one of the factors that increase the risk coefficient;
3. FN or dose-limiting neutropenia events have occurred in previous treatment cycles;
4. In addition to the above, the researchers believe that the medication regimens will cause neutropenia and affect the normal treatment of the subjects; 4. Researchers believe that they can benefit; 5. Voluntarily participate in this clinical trial and be able to sign the informed consent form in person.
Exclusion Criteria:
* 1\. Those who are allergic to the test drug; 2. Those with mental or neurological disorders who are unable to cooperate; 3. Pregnant or lactating female patients; Women of childbearing age who refuse to take contraceptive measures; 4. Those who were considered unsuitable for inclusion by the researchers.
Primary outcome measure(s)
Incidence of FN — From enrollment to the end of treatment 3 weeks later The incidence of neutropenic fever (FN) in the first cycle
Trial sites (1)
Facility
City
Region
Status
HebeiMuFH
Shijiazhuang
Hebei
Recruiting
More Hebei Medical University Fourth Hospital trials in China
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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