🇮🇪Ireland
16°C Partly Cloudy · Dublin
Live Updates
--:--:-- IST
Writer Login
Latest
Clinical Trials in China / NCT07410507
Recruiting Phase 2

A Study of Brenipatide in Adult Participants With Schizophrenia

NCT07410507 · tracked via the Priya Life Science China tracker
Sponsor
Eli Lilly and Company
Phase
Phase 2
Started
2026-02-10
Last updated
2026-09-04

Condition(s) studied

Schizophrenia

Investigational drug(s) / intervention(s)

BrenipatidePlacebo

Brenipatide: Administered SC

Placebo: Administered SC

Study summary

The purpose of this study is to assess the efficacy and safety of brenipatide when administered with standard of care (SoC) compared to placebo plus SoC for treatment of schizophrenia.

The trial is divided into three periods as follows: Screening period will last approximately 1 month, treatment period will last a maximum of 12 months, and the follow up period will last approximately 2 months. The length of time of your study participation may last up to approximately 15 months.

Eligibility

Sex
ALL
Min age
18 Years
Max age
55 Years
Healthy volunteers
No
Inclusion Criteria: * Meet the diagnostic criteria of schizophrenia * Are on a stable standard of care medication regimen for schizophrenia * If the duration of illness is \>6 years, participant has experienced at least one relapse of schizophrenia in last 3 years * Have at least 1 reliable study partner (for example, a family member, social worker, caseworker, residential facility staff, or nurse) * Are reliable and willing to make themselves available for the duration of the study and attend required study visits, and are willing and able to follow study procedures as required, such as * self-inject study intervention store and use the provided study intervention as directed, * maintain electronic or paper study diaries, as applicable, and * complete the required questionnaires Exclusion Criteria: * Have lifetime history of bipolar disorder, borderline personality disorder, or any eating disorder * Evidence of moderate or severe substance or alcohol use disorder within 180 days of screening * Have type 1 diabetes, or history of ketoacidosis or hyperosmolar state or coma * Are actively suicidal or deemed to be a significant risk for suicide * Are currently enrolled in any other clinical study involving an investigational product or any other type of medical research judged not to be scientifically or medically compatible with this study

Primary outcome measure(s)

Trial sites (103)

FacilityCityRegionStatus
Pillar Clinical Research- Little Rock Little Rock Arkansas Recruiting
Clinical Innovations, Inc. dba CITrials Bellflower California Recruiting
Collaborative Neuroscience Research, LLC Garden Grove California Recruiting
Catalina Research Institute, LLC Montclair California Not Yet Recruiting
Stanford University School of Medicine Stanford California Recruiting
Collaborative Neuroscience Research, LLC Torrance California Recruiting
Sunwise Clinical Research Walnut Creek California Recruiting
Institute of Living Hartford Connecticut Recruiting
Yale University School of Medicine New Haven Connecticut Recruiting
Magno Medical Research Group Cooper City Florida Recruiting
NextPhase Research Florida - Hollywood Hollywood Florida Not Yet Recruiting
Innovative Clinical Research Lauderhill Florida Recruiting
Accel Research Sites - Maitland Clinical Research Unit Maitland Florida Recruiting
Wellness Research Center Miami Florida Recruiting
Vital Medical Research Miami Florida Recruiting
CLA Research Naples Florida Recruiting
Apg Research, Llc Orlando Florida Recruiting
Atlanta Center for Medical Research Atlanta Georgia Recruiting
Augusta University Augusta Georgia Recruiting
Re:Cognition Health - Chicago Chicago Illinois Recruiting
CBH Health Gaithersburg Maryland Recruiting
McLean Hospital Belmont Massachusetts Recruiting
Adams Clinical Watertown Watertown Massachusetts Recruiting
University of Massachusetts Chan Medical School Worcester Massachusetts Recruiting
Arch Clinical Trials St Louis Missouri Recruiting
Adams Clinical Harlem New York New York Recruiting
Insight Clinical Trials Independence Ohio Recruiting
University of Oregon Eugene Oregon Recruiting
Adams Clinical Philadelphia Philadelphia Pennsylvania Recruiting
Adams Clinical Dallas DeSoto Texas Recruiting
Re:Cognition Health - Fort Worth Fort Worth Texas Recruiting
Northwest Clinical Research Center Bellevue Washington Recruiting
Centro Neurobiológico y de Estrés Traumático (CENydET) Buenos Aires Argentina Recruiting
Fundación para el Estudio y Tratamiento de Enfermedades Mentales (FETEM) Buenos Aires Argentina Recruiting
Instituto Nacional de Psicopatología (INAPsi)- FunDaMos Buenos Aires Argentina Recruiting
Fundación Cenit Para La Investigación En Neurociencias CABA Argentina Not Yet Recruiting
CEN Centro Especializado en Neurociencias Córdoba Argentina Recruiting
Sanatorio Morra S.A. Córdoba Argentina Not Yet Recruiting
Instituto Kremer Córdoba Argentina Recruiting
Centro Médico Luquez Córdoba Argentina Recruiting

+ 63 more sites — see the full list on the official registry below.

More Eli Lilly and Company trials in China

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07410507 on ClinicalTrials.gov ↗ ← All trials in China