Institute of Hematology & Blood Diseases Hospital, China
Phase
Observational
Started
2025-12-18
Last updated
2026-01-29
Condition(s) studied
Transplant-Related Disorder
Study summary
This is a prospective observational study. The investigators plan to utilize this model as a tool for early classification and interrogate ANS function of transplant recipients.
Eligibility
Sex
ALL
Min age
16 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria:
1. Patients must be \> 16 years of age;
2. Patients receiving HLA-haploidentical transplants;
3. Patients have to sign an informed consent form before the start of the research procedure.
Exclusion Criteria:
1. Tandem transplantation or multiple transplantations;
2. Mental or other medical conditions that make the patients unable to comply with the research treatment and monitoring requirements;
3. Patients who are ineligible for the study due to other factors, or will bear great risk if participating in the study.
Primary outcome measure(s)
Result of heart rate response to standing test — Within one month before the transplantation and during 17-25 days after the transplantation. Autonomic nervous system functional tests including heart rate response to standing will be performed within one month before the transplantation and during 17-25 days after the transplantation.
Result of piloerection test — Within one month before the transplantation and during 17-25 days after the transplantation. Autonomic nervous system functional tests including piloerection will be performed within one month before the transplantation and during 17-25 days after the transplantation.
Number of participants with abnormal dynamic electrocardiography readings — Within one month before the transplantation and during 17-25 days after the transplantation. Dynamic electrocardiography will be performed within one month before the transplantation and during 17-25 days after the transplantation.
Trial sites (1)
Facility
City
Region
Status
Institute of Hematology & Blood Diseases Hospital
Tianjin
Tianjin Municipality
Recruiting
More Institute of Hematology & Blood Diseases Hospital, China trials in China
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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