Evaluation of the Efficacy and Safety of Oral LW402 Tablets for the Treatment of Patients With Moderate-to-Severe Atopic Dermatitis

Inclusion Criteria: * Subjects voluntarily provided informed consent and agreed to participate in the study. * Gender: no restrictions; Age: 18 to 75 years inclusive (as of the date of signing the informed consent form). * At screening, subjects met the Hanifin-Rajka diagnostic criteria for atopic dermatitis (AD) (Appendix 4) and had a documented AD history of ≥1 year prior to screening. * At screening and baseline visits, subjects were required to have moderate-to-severe atopic dermatitis (AD) with all three of the following criteria satisfied: * Total AD lesion area ≥ 10% of body surface area (BSA) * Investigator's Global Assessment (IGA) score ≥ 3 * Eczema Area and Severity Index (EASI) score ≥ 16 Exclusion Criteria: * Subjects with a documented history of hypersensitivity to Janus kinase (JAK) inhibitors. * Subjects with current or a history of autoimmune diseases other than atopic dermatitis (AD) (e.g., systemic lupus erythematosus \[SLE\], inflammatory bowel disease \[IBD\], Felty's syndrome, scleroderma, inflammatory myopathy, other connective tissue diseases, overlap syndrome) or other skin conditions that may interfere with AD assessment (e.g., contact dermatitis, psoriasis).