Intracardiac Echocardiography-Guided Cavotricuspid Isthmus Ablation With a Circular-Shaped Pulsed Field Ablation Catheter

NCT07353775 · tracked via the Priya Life Science China tracker

Sponsor

Beijing Anzhen Hospital

Phase

Observational

Started

2025-01-15

Last updated

2026-01-20

Condition(s) studied

Atrial Fibrillation (AF)Atrial Flutter

Investigational drug(s) / intervention(s)

ICE-guided CTI ablation with PFA

ICE-guided CTI ablation with PFA: Cavotricuspid isthmus ablation with a circular-shaped pulsed field ablation catheter guided by intracardiac echocardiography

Study summary

This observational study aims to evaluate the effectiveness and safety of a circular-shaped pulsed field ablation (PFA) catheter for CTI ablation under the guidance of intracardiac echocardiography (ICE). The main question it aims to answer is:

Is the circular-shaped PFA catheter an effective and safe tool for achieving acute success for CTI ablation? Patients undergoing CTI ablation with a circular-shaped PFA catheter will be prospectively enrolled.

Eligibility

Sex

ALL

Min age

18 Years

Max age

—

Healthy volunteers

Inclusion Criteria: * Paroxysmal or persistent atrial fibrillation * Aged 18 years or older * Scheduled for CTI ablation * Able and willing to provide written informed consent Exclusion Criteria: * Previous CTI ablation * Significant congenital heart disease or structural anomaly affecting the CTI * Active intracardiac thrombus * Pregnancy or lactation * Severe renal/hepatic insufficiency * Active systemic infection or sepsis * Life expectancy of less than 12 months * Unable to provide written informed consent.

Primary outcome measure(s)

Acute Success of CTI Block — Within the ablation procedure
Bidirectional block was assessed immediately after the last ablation application and re-confirmed at the end of the 20-minute observation period.

Trial sites (1)

Facility	City	Region	Status
Beijing Anzhen Hospital	Beijing	China	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07353775 on ClinicalTrials.gov ↗ ← All trials in China