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Clinical Trials in China / NCT07349381
Active, not recruiting Phase 1

A Food-Effect Study of CX11 in Healthy Participants

NCT07349381 · tracked via the Priya Life Science China tracker
Sponsor
Vincentage Pharma Co., Ltd
Phase
Phase 1
Started
2026-03-04
Last updated
2026-09-16

Condition(s) studied

Obesity & OverweightType 2 Diabetes

Investigational drug(s) / intervention(s)

CX11 (VCT220)

CX11 (VCT220): CX11 (VCT220) administered orally to participants who are in fasted/fed state in the first 6 consecutive days, and in fed/fasted state on the 7th day

Study summary

This study is to evaluate the food effect (FE) on the PK of 200 mg CX11 in healthy participants

Eligibility

Sex
ALL
Min age
18 Years
Max age
45 Years
Healthy volunteers
Accepted
Inclusion Criteria: 1. Fully understand the objective, nature, methods, and possible adverse reactions of the study; be able to communicate well with the investigator; voluntarily take part in the study and be willing to comply with the requirements of this study; and sign the informed consent form before all study procedures are started 2. Weight ≥ 50.0 kg for men and ≥ 45.0 kg for women, and body mass index (BMI) is ≥ 20.0 kg/m2 and \< 28 kg/m2 at the screening visit and on Day 21. Exclusion Criteria: 1. Participants with allergic constitution or known previous history of allergy to CX11 or similar compounds and related excipients, or history of atopic allergic diseases 2. Participants who have experienced clinically significant acute diseases during the pre-study screening period or within 2 weeks prior to the first dose of the investigational product 3. Participants who have pre-existing condition interfering with normal gastrointestinal anatomy or motility, hepatic and/or renal function that could affect drug absorption, distribution, metabolism, and/or excretion as judged by the investigator, or plan to receive any surgery during the study 4. Participants suffering from any clinically significant chronic diseases, including but not limited to disorders of the respiratory system, cardiovascular system, urinary system, blood system, endocrine system, and immune system, as well as the digestive system (e.g., history of or current fatty liver disease, including metabolic dysfunction-associated steatohepatitis 5. History of thyroid dysfunction requiring medication or with a thyroid stimulating hormone (TSH) level exceeding the normal reference range at screening or on Day 21 6. Participants who have been vaccinated within 30 days before the screening or plan to be vaccinated during the study 7. Participated in any other clinical study and received an investigational intervention within 90 days or 5 elimination half-lives (whichever is longer) of the investigational intervention, prior to screening

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Shanghai Xuhui Central Hospital Shanghai Shanghai Municipality

More Vincentage Pharma Co., Ltd trials in China

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07349381 on ClinicalTrials.gov ↗ ← All trials in China