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Clinical Trials in China / NCT07335029
Active, not recruiting Observational

Investigation of Hemodynamics and Radiomics Based on High Resolution Magnetic Resonance Imaging for Predicting the Outcomes of Intracranial Dissecting Aneurysm

NCT07335029 · tracked via the Priya Life Science China tracker
Sponsor
Beijing Neurosurgical Institute
Phase
Observational
Started
2023-01-01
Last updated
2026-01-12

Condition(s) studied

Cerebrovascular DiseaseIntracranial AneurysmIntracranial Arterial Dissection

Study summary

This study aims to conduct a comprehensive analysis by integrating clinical factors, aneurysm morphological characteristics, and factors reflecting pathophysiological processes (such as hemodynamic and radiomics features), in order to explore the hemodynamic mechanisms associated with the progression of intracranial dissecting aneurysms. Furthermore, artificial intelligence algorithms will be employed to develop and validate an intelligent risk prediction model for the progression and outcomes of intracranial dissecting aneurysms.

Eligibility

Sex
ALL
Min age
18 Years
Max age
80 Years
Healthy volunteers
No
Inclusion Criteria: 1. Intracranial dissecting aneurysm clearly diagnosed by DSA and high-resolution MRI imaging (according to the imaging diagnostic criteria proposed in the Chinese Expert Consensus on Imaging Diagnosis of Intracranial Arterial Dissection) 2. patients managed with conservative treatment and follow-up 3. patients who agree and sign a written informed consent form Exclusion Criteria: 1. Arteritis, fibromuscular dysplasia, iatrogenic or traumatic pseudoaneurysms 2. Contraindications to MRI examination (such as claustrophobia or metallic implants), or contraindications to cerebral angiography (such as iodine contrast allergy) 3. Dissecting aneurysms extending from the extracranial segment to the intracranial segment, or cases with concomitant intracranial atherosclerotic plaques in the affected vessels 4. Patients who refuse MRI examination 5. Patients with severe comorbid diseases and an expected survival time of less than 2 years due to these conditions 6. Patients without follow-up HR-MRI imaging for any reason

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Beijing Tiantan Hospital, Capital Medical University Beijing Beijing Municipality

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07335029 on ClinicalTrials.gov ↗ ← All trials in China