Investigation of Hemodynamics and Radiomics Based on High Resolution Magnetic Resonance Imaging for Predicting the Outcomes of Intracranial Dissecting Aneurysm
This study aims to conduct a comprehensive analysis by integrating clinical factors, aneurysm morphological characteristics, and factors reflecting pathophysiological processes (such as hemodynamic and radiomics features), in order to explore the hemodynamic mechanisms associated with the progression of intracranial dissecting aneurysms. Furthermore, artificial intelligence algorithms will be employed to develop and validate an intelligent risk prediction model for the progression and outcomes of intracranial dissecting aneurysms.
Eligibility
Sex
ALL
Min age
18 Years
Max age
80 Years
Healthy volunteers
No
Inclusion Criteria:
1. Intracranial dissecting aneurysm clearly diagnosed by DSA and high-resolution MRI imaging (according to the imaging diagnostic criteria proposed in the Chinese Expert Consensus on Imaging Diagnosis of Intracranial Arterial Dissection)
2. patients managed with conservative treatment and follow-up
3. patients who agree and sign a written informed consent form
Exclusion Criteria:
1. Arteritis, fibromuscular dysplasia, iatrogenic or traumatic pseudoaneurysms
2. Contraindications to MRI examination (such as claustrophobia or metallic implants), or contraindications to cerebral angiography (such as iodine contrast allergy)
3. Dissecting aneurysms extending from the extracranial segment to the intracranial segment, or cases with concomitant intracranial atherosclerotic plaques in the affected vessels
4. Patients who refuse MRI examination
5. Patients with severe comorbid diseases and an expected survival time of less than 2 years due to these conditions
6. Patients without follow-up HR-MRI imaging for any reason
Primary outcome measure(s)
Progression of intracranial dissecting aneurysms — From enrollment to 12 months of follow-up
Trial sites (1)
Facility
City
Region
Status
Beijing Tiantan Hospital, Capital Medical University
Beijing
Beijing Municipality
More Beijing Neurosurgical Institute trials in China
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
We use cookies to analyse site traffic and improve your experience. With your consent, we may also use cookies for advertising. You can change your choice at any time on our Cookie Policy page. See also our Privacy Policy.