🇮🇪Ireland
16°C Partly Cloudy · Dublin
Live Updates
--:--:-- IST
Writer Login
Latest
Clinical Trials in China / NCT07319546
Recruiting Not applicable

Accelerated Rehabilitation in Individuals After Total Knee Arthroplasty

NCT07319546 · tracked via the Priya Life Science China tracker
Sponsor
Mahidol University
Phase
Not applicable
Started
2025-12-01
Last updated
2026-01-06

Condition(s) studied

Knee OsteoarthristisArthroplasties, Knee Replacement

Investigational drug(s) / intervention(s)

Accelerated exerciseRoutine exercise

Accelerated exercise: Based on optimal and accelerated concepts

Routine exercise: Conventional program

Study summary

The primary aim of this double-blind randomized controlled trial is to evaluate the effectiveness of an accelerated rehabilitation protocol on knee joint function and quality of life in individuals undergoing TKA compared to conventional rehabilitation in Dali, Yunan, China. The study will include patients aged 50-80 years who are scheduled for primary unilateral TKA. Participants will be randomly assigned to either an accelerated rehabilitation group or conventional rehabilitation group. The primary outcomes will include knee joint function, assessed using the KOOS and quality of life measures using the SF-36 surveys. The study will follow participants for 6 months post-surgery to assess longer-term outcomes. This study will not include individuals undergoing revision TKA or those with severe comorbid conditions. The results will provide critical insights into the role of accelerated rehabilitation in improving post-operative recovery, functional outcomes, and overall quality of life for TKA patients.

Eligibility

Sex
ALL
Min age
50 Years
Max age
80 Years
Healthy volunteers
No
Inclusion Criteria: * Patients diagnosed with end-stage knee OA necessitating primary unilateral TKA. Exclusion Criteria: * History of joint infections, cancer, or inflammatory arthritis. * End-stage OA from rheumatoid or septic arthritis. * Individuals with neurological disorders such as Alzheimer's disease, - Parkinson's disease, stroke. * Individuals who are unable to follow a structured rehabilitation protocol. * Previous history of knee surgeries (other than arthroscopy). * Severe comorbidities that would hinder participation (e.g., advanced cardiovascular diseases). * Individuals who have severe osteoporosis.

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Hospital Dali Yunnan Recruiting

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07319546 on ClinicalTrials.gov ↗ ← All trials in China