Elderly Patients Undergoing Surgery During Perioperative Period

NCT07314762 · tracked via the Priya Life Science China tracker

Sponsor

Second Affiliated Hospital of Wenzhou Medical University

Phase

Observational

Started

2023-12-30

Last updated

2026-04-01

Condition(s) studied

Postoperative ComplicationsElderlyPostoperative Delirium (POD)Risk Prediction ModelPathogenesis

Study summary

The elderly patients have poorer overall conditions and have lower tolerance to trauma, anesthesia, and surgery. Therefore, the incidence of postoperative complications is relatively higher. In non-cardiac surgeries, approximately 20% of elderly patients experience postoperative complications, and the incidence of postoperative delirium (POD) is 23.8%. This may lead to prolonged hospital stays, increased hospital costs, and affect prognosis and even mortality. The investigators plan to conduct a prospective cohort study by systematically collecting biological samples and clinical information of elderly patients during the perioperative period to explore the possible risk factors and pathogenesis of postoperative delirium and postoperative complications in elderly surgical patients, and to construct a risk prediction model for postoperative complications.

Eligibility

Sex

ALL

Min age

65 Years

Max age

—

Healthy volunteers

Accepted

Inclusion Criteria: 1\) Surgical patients aged 65 or above or non-surgical subjects aged 65 or above. 2) Agree to participate in this study and sign the informed consent form. Exclusion Criteria: 1）Refused to participate in the study.

Primary outcome measure(s)

Incidence of postoperative delirium (POD) within 7 days after surgery — Preoperative, during the first 7 postoperative days
POD is diagnosed daily using the Three-Minute Diagnostic Confusion Assessment Method (3D-CAM).

Trial sites (1)

Facility	City	Region	Status
The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University	Wenzhou	Zhejiang	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07314762 on ClinicalTrials.gov ↗ ← All trials in China