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Clinical Trials in China / NCT07309926
Starting soon Observational

Gait and Paraspinal sEMG in Degenerative Spinal Diseases

NCT07309926 · tracked via the Priya Life Science China tracker
Sponsor
Xuanwu Hospital, Beijing
Phase
Observational
Started
2025-12-10
Last updated
2025-12-30

Condition(s) studied

Adult Spinal DeformityDegenerative ScoliosisSagittal DeformitySagittal ImbalanceCoronal Vertical AxisLumbar Spinal StenosisLumbar Disc HerniationCervical Spondylosis With Myelopathy

Investigational drug(s) / intervention(s)

Gait analysis and surface electromyography analysis

Gait analysis and surface electromyography analysis: A comprehensive motion analysis system was employed to assess biomechanical parameters during functional tasks. Ground reaction forces (GRFs) were measured using an instrumented force plate, while muscle activation patterns were recorded via surface electromyography (sEMG). Three-dimensional kinematic data were concurrently captured using motion-capture cameras. The standardized testing protocol consisted of: (1) quiet standing (30-second trial) and (2) three consecutive back-and-forth walking cycles (5-meter walkway), enabling the quantification of both static postural control and dynamic gait characteristics.

Study summary

This cross-sectional observational study aims to quantitatively compare three-dimensional gait parameters, surface electromyography (EMG) patterns, and radiological parameters among patients with different degenerative spinal conditions-including lumbar disc herniation (LDH), lumbar spinal stenosis (LSS), lumbar sagittal imbalance (LSI), degenerative lumbar scoliosis (DLS), and cervical spondylotic myelopathy (CSM)-alongside a healthy control group. The analysis focuses on spatiotemporal gait characteristics (step length, stride length, cadence), lower limb kinematics and kinetics (hip/knee/ankle joint angles, moments, and powers during stance and swing phases), and surface EMG amplitudes (thoracic erector spinae, multifidus, gluteus maximus, and rectus abdominis muscles) during standardized walking tasks. Additionally, radiological parameters (e.g., pelvic incidence-lumbar lordosis mismatch, C2-C7 sagittal vertical axis, coronal Cobb angle) will be correlated with gait and muscle activation deviations. The study employs motion capture systems, force plates, and high-density EMG to objectively differentiate disease-specific movement impairments. Findings from this study may establish biomechanical and neuromuscular signatures for each degenerative condition, providing a framework for personalized rehabilitation strategies, gait retraining, and surgical outcome assessment in spinal disorders. Comparative analysis with healthy controls will further elucidate pathological alterations in gait and muscle recruitment patterns caused by degenerative spinal diseases.

Eligibility

Sex
ALL
Min age
60 Years
Max age
Healthy volunteers
Accepted
Inclusion Criteria: 1. Patients with the following single disease: degenerative scoliosis, coronal imbalance, lumbar spinal stenosis, lumbar disc herniation, spinal cord-type cervical spondylosis; 2. Age ≥ 60 years, regardless of gender; 3. Planned to undergo elective open spinal fusion surgery; 4. Voluntarily participate in the study, understand and agree to the study content, and sign the informed consent form. Exclusion Criteria: 1. History of previous spinal surgery; 2. Combined with other neuromuscular diseases (such as Parkinson's disease), inflammatory diseases (such as ankylosing spondylitis), infectious diseases (such as spinal tuberculosis), sepsis, tumors, or lower limb joint diseases that may cause low back and lower limb pain, affecting physical activity; 3. Suffering from severe cardiovascular, cerebral, liver, or kidney disease; 4. Suffering from mental illness, dementia, or unable to cooperate to complete clinical research. * Skin rupture in the waist;

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Xuanwu Hospital Capital Medical University Beijing Beijing Municipality

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07309926 on ClinicalTrials.gov ↗ ← All trials in China