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Clinical Trials in China / NCT07297797
Active, not recruiting Phase 2

Phase II Clinical Study of HRS-9563 in Patients With Mild to Moderate Hypertension

NCT07297797 · tracked via the Priya Life Science China tracker
Sponsor
Fujian Shengdi Pharmaceutical Co., Ltd.
Phase
Phase 2
Started
2026-01-14
Last updated
2026-07-31

Condition(s) studied

Mild to Moderate Hypertension

Investigational drug(s) / intervention(s)

HRS-9563 Injectionsodium chloride injection

HRS-9563 Injection: HRS-9563 Injection

sodium chloride injection: sodium chloride injection

Study summary

This study aims to evaluate the efficacy and safety of HRS-9563 in patients with mild to moderate hypertension, and to explore its appropriate dosage.

Eligibility

Sex
ALL
Min age
18 Years
Max age
75 Years
Healthy volunteers
No
Inclusion Criteria: 1. The subject voluntarily signs the informed consent form. 2. Male or female, aged ≥ 18 years and ≤ 75 years; 3. Patients with mild to moderate hypertension; 4. At the Screening and Baseline periods, the mean sitting office systolic blood pressure is \> 130 mmHg, and the 24-hour mean systolic blood pressure assessed by ABPM at Screening is ≥ 130 mmHg and \< 160 mmHg. Exclusion Criteria: 1. Secondary hypertension; 2. Orthostatic hypotension; 3. Type 1 diabetes or poorly controlled type 2 diabetes; 4. Occurrence of any cardiovascular or cerebrovascular event within 6 months prior to screening; 5. Presence of uncontrolled severe arrhythmia within 6 months prior to screening; 6. Suspected allergy to the investigational drug or any of its components; 7. Other diseases requiring Renin-Angiotensin-Aldosterone System (RAAS) inhibitor therapy, besides hypertension; 8. Any blood biochemical indicator during screening or baseline did not meet the standards in the exclusion criteria; 9. Use of any medication affecting blood pressure within 4 weeks prior to screening, or planned use during the study period;

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Beijing Anzhen Hospital, Capital Medical University Beijing Beijing Municipality

More Fujian Shengdi Pharmaceutical Co., Ltd. trials in China

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07297797 on ClinicalTrials.gov ↗ ← All trials in China