The integrity and functional stability of pharyngolaryngeal anatomical structures are critical for airway management, and the dynamic changes of key structures (e.g., pyriform sinus, cricoid cartilage lamina) during swallowing directly relate to the design and clinical safety of laryngeal masks. This observational study aims to investigate the real-time dynamic changes and physiological movement patterns of normal pharyngolaryngeal structures during barium swallow using routine barium meal examination imaging. The findings will provide anatomical and physiological evidence for optimizing laryngeal mask design and improving its anatomical fit with the pharynx and larynx.
Eligibility
Sex
ALL
Min age
18 Years
Max age
75 Years
Healthy volunteers
No
Inclusion Criteria:
* Aged 18-75 years;
* No history of pharyngolaryngeal surgery, trauma, or congenital malformation;
* No swallowing dysfunction, pharyngolaryngeal inflammation, or neurological diseases affecting swallowing;
* No recent use of drugs that affect muscle function (e.g., muscle relaxants, anticholinergics);
* Barium meal examination confirms unobstructed oropharyngeal-esophageal pathway;
* Normal pharyngolaryngeal anatomical structure (confirmed by preliminary imaging review);
* Scheduled to undergo routine barium meal examination at Zhejiang Cancer Hospital for clinical diagnosis.
Exclusion Criteria:
* Presence of diseases that may compress pharyngolaryngeal structures (e.g., goiter, mediastinal mass);
* Allergy to barium sulfate or other components of the barium suspension.
Primary outcome measure(s)
Real-time dynamic changes of pharyngolaryngeal structures during swallowing — From the initiation of the barium swallow to the complete passage of the bolus through the upper esophageal sphincter, as assessed under videofluoroscopy (an average of 15 minutes per participant). Measurement of displacement distance of the cricoid cartilage lamina, expansion amplitude of the pyriform sinus, and movement trajectory of the esophageal inlet during swallowing (assessed via dynamic fluoroscopic imaging).
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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