A Multi-center Retrospective Study of INO Treating B-ALL

Inclusion Criteria: * Age between ≥16 and ≤80 years at screening, no gender restrictions * Be diagnosed with B-ALL * Appropirate organ function, meeting the following criteria: 1. Aspartate aminotransferase (AST) ≤3 times the upper limit of normal (ULN); 2. Alanine aminotransferase (ALT) ≤3 times ULN; 3. Total bilirubin ≤2 times ULN (for patients with Gilbert's syndrome, total bilirubin ≤3.0 times ULN and direct bilirubin ≤1.5 times ULN); 4. Serum creatinine ≤1.5 times ULN, or creatinine clearance ≥60 mL/min (using the Cockcroft-Gault formula); 5. Left ventricular ejection fraction (LVEF) ≥50%; Exclusion Criteria: * Active infection at screening. * Any of the following cardiac conditions: 1. NYHA Class III or IV congestive heart failure; 2. Severe arrhythmia requiring treatment; 3. Uncontrolled hypertension or pulmonary hypertension despite standard therapy; 4. Unstable angina; 5. Myocardial infarction, bypass surgery, or stent placement within six months before cell retransfusion; 6. Clinically significant valvular disease; 7. Other cardiac conditions deemed unsuitable by the investigator; * History of epilepsy, cerebellar disease, or other active central nervous system disorders; * History of hypersensitivity to any component of the investigational product. * Life expectancy of less than three months; * Other conditions deemed unsuitable for participation in this clinical trial by the investigator.