Autologous Non-cultured Epidermal Cell Suspension Transplantation in the Treatment of Vitiligo

Condition(s) studied

Investigational drug(s) / intervention(s)

Autologous Non-cultured Epidermal Cell Suspension transplantation: 1. Thin split thickness skin grafts were taken from the donor site (anterolateral thigh) after application of topical anaesthesia under complete aseptic precautions. 2. The cell suspension was prepared by the cell sorting kit (Primcell, Jiangsu Repatec Life Science Co.,Ltd). 3. Then the recipient skin was uniformly dermabraded using an electrical dermabrader set at 10,000 to 20,000 rpm until punctate bleeding points appeared. 4. The cell suspension was applied onto the dermabraded recipient area. 5. The recipient site was then fixed firmly with dressings and elastic bandage. The dressings were removed 10 days after transplantation.

Study summary

To observe the long-term efficacy and safety of autologous non cultured epidermal cell suspension transplantation in the treatment of vitiligo, analyze the correlation between cell density, type, and postoperative efficacy and prognosis, and providing a basis for clinical application.

Eligibility

Primary outcome measure(s)

• Repigmentation rate — 2 weeks, 1month, 2 months, 3 months, 4 months, 5 months and 6 months after transplantation
  The repigmentation rate depends on the percentage of repigmentation area /recipient area\*100%. The extent of repigmentation was devided as poor (less than 25%), good (26%-50%), very good (51%-75%), or excellent (more than75%).

Trial sites (1)

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