Local Anaesthetic Spread and Sensory Block Range of the Retro-superior Costotransverse Ligament Space Block

NCT07153263 · tracked via the Priya Life Science China tracker

Sponsor

Nanjing First Hospital, Nanjing Medical University

Phase

Not applicable

Started

2025-09-12

Last updated

2026-08-28

Condition(s) studied

Pulmonary NodulesNerve Block

Investigational drug(s) / intervention(s)

Ultrasound-guided retro-SCTLBUltrasound-guided TPVB

Ultrasound-guided retro-SCTLB: Patients undergoing CT-guided lung nodule localization were selected for the study. Before the surgery, the retro-SCTLB was performed under ultrasound guidance.

Ultrasound-guided TPVB: Patients undergoing CT-guided lung nodule localization were selected for the study. Before the surgery, the TPVB was performed under ultrasound guidance.

Study summary

The aim of this clinical trial is to investigate the effects of local anesthetic diffusion range and sensory block range during retro-SCTLB(retro superior costotransverse ligament space block) and TPVB(thoracic paravertebral block) in patients undergoing CT-guided lung nodule localization. The main issue of the study is to determine the differences in the diffusion range and sensory block range of local anesthetics between the retro-SCTLB and TPVB nerve block methods.

Eligibility

Sex

ALL

Min age

18 Years

Max age

80 Years

Healthy volunteers

Inclusion Criteria: Patients scheduled for CT-guided lung nodule localization under local anesthesia will be selected 1. aged 18-80 years 2. BMI 18-30 kg/m² 3. ASA classification I-III Exclusion Criteria: 1. Allergy to the study drug or local anesthetic; 2. History of opioid abuse; 3. Pre-existing skin infection at the puncture site of ITPN or TPVB; 4. Peripheral infectious neuropathy; 5. Dysfunction of blood coagulation

Primary outcome measure(s)

Spread of local anesthetic into the paravertebral space — 15 minutes after completion of the nerve block
Observation of incidence and thoracic level of local anesthetic spread into the paravertebral space with CT by a researcher who was blinded to group allocation

Trial sites (2)

Facility	City	Region	Status
Tao Shan	Nanjing	Jiangsu	Recruiting
Nanjing First Hospital	Nanjing	China	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07153263 on ClinicalTrials.gov ↗ ← All trials in China