The Impact of the Adequacy of Keratinized Mucosa on Peri-implant Tissue Health and Patient-reported Outcomes

Condition(s) studied

Investigational drug(s) / intervention(s)

No intervention: No intervention: observational case-control study

Study summary

This study aims to conduct a cross-sectional study to compare the differences in clinical indices, patient-reported outcomes, and levels of inflammatory factors in peri-implant gingival crevicular fluid between sites with adequate (≥ 2 mm) and inadequate (\< 2 mm) keratinized mucosa after implant restoration, in order to explore the impact of the presence of keratinized mucosa on peri-implant soft and hard tissue health.

Eligibility

Primary outcome measure(s)

• Width of Keratinized Mucosa, KMW — on the day of enrollment
• Plaque Index(PI) — on the day of enrollment
• Bleeding on Probing(BOP) — on the day of enrollment
• Peri-implant Probing Depth(PPD) — on the day of enrollment
• Marginal Bone Loss(MBL) — The X-ray examination will be completed on the day of enrollment
• Patient Satisfaction — on the day of enrollment
  visual analogue scale \[VAS\] 0-10,e.g., not at all satisfied to perfectly satisfied
• Immunological parameters in peri-implant crevicular fluids(PICF) — The PICF will be collected on the day of enrollment
  PICF samples were collected from buccal aspects of implants after removing all supragingival plaque. The levels of IL-1β and PGE2 in PICF were measured using a sandwich ELISA kit.

Trial sites (1)