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Clinical Trials in China / NCT07106268
Active, not recruiting Observational

Aqueous Humor Proteome in Retinal Vein Occlusion With Macular Edema

NCT07106268 · tracked via the Priya Life Science China tracker
Sponsor
Tianjin Medical University Eye Hospital
Phase
Observational
Started
2023-03-01
Last updated
2025-08-07

Condition(s) studied

Retinal Vein Occlusion

Study summary

the goal of this observational study is to the find the molecular mechanisms underlying the prognosis process of Retinal vein occlusion in patients with retinal vein occlusion . The main question it aims to answer is:

What are the changes in protein in the aqueous humor during treatment in patients who are sensitive to anti-VEGF drug therapy?

Eligibility

Sex
ALL
Min age
20 Years
Max age
80 Years
Healthy volunteers
Accepted
Inclusion Criteria: * Cystic or diffuse edema in the macular area, retinal vein tortuous dilation with hemorrhage * Optical coherence tomography (OCT) examination showed that the macular area was raised, edema and thickened * Monocular disease, baseline central retinal thickness (CRT) ≥ 250mm * Intravitreal injection, laser photocoagulation and blood circulation and blood stasis removal drugs were not treated before surgery * The patient had normal blood pressure, negative urine protein, normal liver and kidney function, and normal electrocardiogram Exclusion Criteria: * Patients with fluorescein fundus angiography (FFA) showing a large area (10 optic disc areas) without perfusion requiring retinal photocoagulation * Patients with chronic dacryocystitis, glaucoma, cataract, severe proliferative vitreoretinopathy or vitreous hemorrhage, epi macular membrane or macular ischemia, diabetic retinopathy, age-related macular degeneration, ocular trauma and other diseases * Intravitreal therapy or laser photocoagulation with corticosteroids or anti-VEGF drugs within three months before the study

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Tianjin medical university eye hospital Tianjin Province

More Tianjin Medical University Eye Hospital trials in China

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07106268 on ClinicalTrials.gov ↗ ← All trials in China