Golidocitinib Combined With Mitoxantrone Hydrochloride Liposome or Chidamide in the Treatment of Relapsed or Refractory Peripheral T-cell Lymphoma
Condition(s) studied
Investigational drug(s) / intervention(s)
Golidocitinib: 150mg, po, qd;
Mitoxantrone Hydrochloride Liposome: Cohort 1: 15 mg/m2, IV, D1 and 18 mg/m2, IV, D1 (phase Ib); RP2D (II study)
Chidamide: Cohort 2: Chidamide:20mg/30mg, po, Biw (phase Ib); RP2D (phase II study)
Study summary
This is a prospective, multicenter, open-label, phase Ib/II clinical study to evaluate the safety and efficacy of golidocitinib combined with mitoxantrone hydrochloride liposome or chidamide in the treatment of relapsed or refractory peripheral T-cell lymphoma
Eligibility
Primary outcome measure(s)
- Overall response rate(ORR) for Phase 2 — Up to 24 months
The proportion of patients who achieve complete remission (CR) or partial remission (PR) as the best response. - Maximum tolerated dose (MTD) for Phase 1b — The first cycle after administration
To identify the MTD
Trial sites (1)
| Facility | City | Region | Status |
|---|---|---|---|
| Sun Yat-sen Universitiy Cancer Center, Sun Yat-Sen University | Guangzhou | Guangdong | Recruiting |
More Sun Yat-sen University trials in China
Other trials for the same condition
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT07093710 on ClinicalTrials.gov ↗ ← All trials in China