Effects of Non-Invasive Superficial Craniocervical Lymphatic Drainage (NSCLD) on Memory and Cognitive Function in Adults With Sleep Deprivation: A Proof-of-Concept Study
Non-Invasive Superficial Craniocervical Lymphatic Drainage (NSCLD): Participants will be randomly assigned to either an intervention group receiving NSCLD or a control group receiving a sham-intervention treatment. Cognitive function will be assessed using standardized tests before and after the intervention.
sham-intervention treatment: Participants will be randomly assigned to either an intervention group receiving NSCLD or a control group receiving a sham-intervention treatment. Cognitive function will be assessed using standardized tests before and after the intervention.
Study summary
This Effects of Non-Invasive Superficial Craniocervical Lymphatic Drainage (NSCLD) on Memory and Cognitive Function in Adults with Sleep deprivation: A Proof-of-Concept Study aims to investigate the effects of Non-Invasive Superficial Craniocervical Lymphatic Drainage (NSCLD) on memory and cognitive function in adults experiencing sleep deprivation(SD). Given the known impact of SD on cognitive performance, this study seeks to explore whether NSCLD, as a non-invasive intervention, can mitigate the cognitive impairments associated with SD.
Eligibility
Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
Accepted
Inclusion Criteria:
* College student ≥18 years, all of whom have passed a standardized entrance examination;
* No failed exams during the course of study;
* Sleep deprivation;
* In good health, with no mental or psychological disorders;
* No recent use of medications that may affect memory and cognition;
* Voluntary participation and able to undergo cognitive function and memory testing;
* Informed consent provided
Exclusion Criteria:
* Pregnant or breastfeeding women.
* Presence of acute or chronic medical conditions (e.g., severe hypertension, diabetes, cardiovascular disease) that could confound the results.
* History of craniocervical trauma or surgery.
* Current use of sedative or anxiolytic medications that could influence sleep or cognitive function.
* Participants who are unable to follow the procedures or complete the assessments
Primary outcome measure(s)
Digit Span Test — Day 1 (Baseline) and Day 2, repeat after a 2-week washout period Evaluate memory function. 1 point for each correct string of numbers. Total score: forward score + backward score. Higher scores mean a better outcome.
Montreal Cognitive Assessment (MoCA) — Day 1 (Baseline) and Day 2, repeat after a 2-week washout period The maximum score is 30 points. ≥26 points is normal. Higher scores mean a better outcome.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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