Comparison of Drainage Methods in Minimally Invasive Esophagectomy (DEMURE）

Condition(s) studied

Investigational drug(s) / intervention(s)

Chest mediastinal tube: Transthoracic mediastinal drainage was performed for postoperative management of the patient.

Abdominal mediastinal tube: Transperitoneal mediastinal drainage was performed for postoperative management of the patient.

Chest tube + chest mediastinal tube: Chest tube insertion combined with transthoracic mediastinal drainage was performed for postoperative management of the patient.

Study summary

This RCT compares three drainage approaches after minimally invasive esophagectomy (chest tube + thoracic mediastinal drainage tube, thoracic, and abdominal mediastinal drainage tube) to evaluate perioperative outcomes, addressing current evidence gaps in pain and complication profiles.

Eligibility

Primary outcome measure(s)

• Postoperative Pain Scores — Pain scores were recorded at different times during the postoperative period when the patients were quiet and active (at 7 AM, 11 AM, 3 PM, and 7 PM) from postoperative day 1 to postoperative day 4.
  Pain scores were assessed based on the visual analog scale according to the World Health Organization guidelines, in which 0 indicated no pain and 10 indicated the worst possible pain. We also recorded and evaluated maximum daily pain scores when pain caused by the mediastinal drainage tube incision.

Trial sites (1)

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