vegan and omnivorous diet: Participants underwent a 2-week omnivorous diet intervention, followed by a 2-week vegan diet intervention
Study summary
The goal of this interventional study is to investigate how vegan diet affects health in healthy volunteers, Men and women ages 20 - 30 years old. The main questions it aims to answer are:
Change in Microbial community composition and metabolic alterations Changes in plasma metabolic profile. Researchers will compare changes in microbiota and plasma metabolites profile to see the influence of vegan diet in health. In the dietary trial, participants were first assigned to a 2-week omnivorous diet phase, then switched to a 2-week vegetarian diet phase
Eligibility
Sex
ALL
Min age
20 Years
Max age
30 Years
Healthy volunteers
Accepted
Inclusion Criteria: healthe Participants, ages 20-30 years old
Exclusion Criteria:
1. Oral antibiotic use or acute/chronic inflammation within the past 3 months;
2. Hormone intake within the past 3 months;
3. Use of any known interfering medications (e.g., insulin, glibenclamide, indomethacin, phentolamine, furosemide, phenytoin sodium, cortisone, etc.) or probiotics within the past month that may affect glucose or lipid metabolism;
4. Smoking or alcohol consumption;
5. Uncontrolled mental disorders (including a history of psychiatric hospitalization);
6. Currently participating in a weight loss or weight management program;
7. Following a special or medically prescribed diet (e.g., for celiac disease);
8. Comorbid cardiac or renal insufficiency;
9. Chronic constipation;
10. Hypertension;
11. Diabetes mellitus.
Primary outcome measure(s)
Gut microbiota composition in twenty participants — 14days，28days 16S rDNA sequencing technology was used to identify the structural and functional changes of intestinal microbiota before and after vegan diet.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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