underwater endoscopic mucosal resection: The Pedunculated colorectal polyps less than 10mm in size in this group will be treated by UEMR
Hot snare polypectomy: The Pedunculated colorectal polyps less than 10mm in size in this group will be treated by HSP
Study summary
A prospective, single-center, open-label, randomized controlled study to compare the effectiveness and safety of underwater endoscopic mucosal resection (UEMR) and hot snare polypectomy (HSP) in treating Pedunculated colorectal polyps less than 10mm in size.
Eligibility
Sex
ALL
Min age
35 Years
Max age
80 Years
Healthy volunteers
No
Inclusion Criteria:
* Aged between 35 and 80 years
* Pedunculated colorectal polyps less than 10mm in size in screening, surveillance or therapeutic colonoscopy
* 0-Isp or 0-Ip according to Paris classification
* Patients must sign an informed consent form prior to registration in study
Exclusion Criteria:
* Unsuitable for removal by UEMR or HSP
* Suspected malignancy
* History of inflammatory bowel disease or colorectal resection
* Familial adenomatous polyposis or Lynch syndrome
* Patients taking anticoagulant and antiplatelet agents before the examination
* Inadequate bowel preparation, defined as a Boston Bowel Preparation Scale score \< 6
* ASA \>=3
* Pregnancy or breastfeeding
* Severe comorbid disease involving the heart, lungs, liver, or kidneys.
* Concurrent serious conditions, including other active malignancies or severe infectious diseases
Primary outcome measure(s)
Post-polypectomy Bleeding — 2 weeks after the procedure Presence of Clinically Significant Immediate Post-polypectomy Bleeding（CSIPB） or Clinically Significant Delayed Post-polypectomy Bleeding (CSDPB). CSIPB was defined as any bleeding not responding to water jet irrigation or STSC and therefore requiring either coagu lation forceps or mechanical clips to achieve hemostasis. CSDPB was defined as any bleeding after completion of the procedure requiring emergency room presentation, hospital isation or re-intervention (endoscopy, angiography, surgery).
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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