Impact of Ultraviolet Radiation and Environmental Factors on Human Ocular Biomechanics

Condition(s) studied

Investigational drug(s) / intervention(s)

environment Exposure: No special intervention

Study summary

This observational study aims to explore whether ultraviolet (UV) radiation and other environmental factors are associated with ocular biomechanical properties in healthy volunteers aged 18-44 years without ocular diseases, ocular surgery history, or systemic diseases.

The main questions it aims to answer are:

Is there a significant correlation between UV radiation levels and corneal biomechanical parameters?

Do environmental factors such as geographic region and seasonal variation affect corneal biomechanical behavior?

Researchers will compare ocular biomechanical parameters among populations from different geographic regions with varying levels of UV radiation to determine whether there are statistically significant correlations or differences.

Participants will:

Undergo standardized ophthalmic examinations, including visual acuity, intraocular pressure, slit-lamp evaluation, axial length, and corneal topography;

Receive corneal biomechanical assessments using the Corvis ST device;

Provide basic demographic information and medical history;

Have all data de-identified, with the study strictly following ethical approval and privacy protection protocols.

Eligibility

Primary outcome measure(s)

• Corneal Biomechanical Parameters Measured by Corvis ST — Baseline (at time of examination)
  Central corneal thickness (CCT) mm
• Corneal Biomechanical Parameters Measured by Corvis ST — Baseline (at time of examination)
  ,biomechanically corrected intraocular pressure (bIOP) mmHg

Trial sites (1)

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