The Effect of Cap-assisted Water Exchange Colonoscopy on Straight Passage of the Colonoscope Through the Sigmoid Colon, Without Loop Formation

NCT06992856 · tracked via the Priya Life Science China tracker

Sponsor

Fudan University

Phase

Not applicable

Started

2025-06-01

Last updated

2025-05-28

Condition(s) studied

Colonoscope Passage

Investigational drug(s) / intervention(s)

Conventional colonoscope passageleft colon water exchange colonoscope passagecap-assisted left colon water exchange colonoscope passage

Conventional colonoscope passage: Use conventional colonoscope passage through the sigmoid colon

left colon water exchange colonoscope passage: Use left colon water exchange colonoscope passage through the sigmoid colon

cap-assisted left colon water exchange colonoscope passage: Use cap-assisted left colon water exchange colonoscope passage through sigmoid colon

Study summary

A prospective, single-center, single-blind, randomized controlled study to compare the proportion of straight passage through the sigmoid colon without loop formation between conventional colonoscope passage, left colon water exchange colonoscope passage, and cap-assisted left colon water exchange colonoscope passage through the sigmoid colon

Eligibility

Sex

ALL

Min age

18 Years

Max age

80 Years

Healthy volunteers

Inclusion Criteria: * aged 18-80 years * sedation colonoscopy Exclusion Criteria: * History of colorectal surgery * Clinical suspicion of, or pathologically confirmed, colorectal cancer * Presence of any "alarm" symptom or sign-hematochezia, melena, unexplained anemia or weight loss, palpable abdominal mass, or a positive digital rectal examination * Pregnancy or lactation * Known or suspected gastrointestinal obstruction * Diagnosed inflammatory bowel disease * Use of antiplatelet or anticoagulant therapy (e.g., aspirin, warfarin) within 7 days before colonoscopy or any documented coagulation disorder * Current enrolment in another clinical study or participation in any clinical trial within the previous 60 days * Requirement for emergency colonoscopy * Any other condition that, in the investigators' judgment, renders the patient unsuitable for inclusion in the study

Primary outcome measure(s)

The proportion of straight passage through the sigmoid colon without loop formation — immediately after the procedure

Trial sites (1)

Facility	City	Region	Status
Huadong hospital affiliated to Fudan university	Shanghai	Shanghai Municipality

More Fudan University trials in China

The Safety and Efficacy of Multimodal Thermal Therapy in the Treatment of Early-stage Invasive Breast Cancer Starting soon

Comparing the Efficacy of Sintilimab Plus Nab-POF Regimen, Sintilimab Plus XELOX Chemotherapy, and Lenvatinib, Sintilimab Plus XELOX Chemotherapy in the Treatment of HER2-negative, Metastatic Gastric Cancer Starting soon

an AI-Driven Four-Tier Invasion Depth Classification for Early Esophageal Cancer Active, not recruiting

Pucotenlimab Combined With Becotatug Vedotin in Advanced Cutaneous Squamous Cell Carcinoma Starting soon

CDK4/6 Inhibitors Combined With Standard Adjuvant Endocrine Therapy in High-Risk, HR+/HER2+ Early Breast Cancer Patients(CHESS) Recruiting

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06992856 on ClinicalTrials.gov ↗ ← All trials in China