The Efficacy and Adverse Reactions of Neotetracycline in the Treatment of GNB Infections

Condition(s) studied

Investigational drug(s) / intervention(s)

bronchoscope: We will perform bronchoscopy and collect bronchoalveolar lavage fluid(BALF)

Study summary

A multicenter, retrospective, real-world stduy . Subjects with composite criteria were teated with eravacycline ,and 100 cases ,Tigecycline and 300 cases were to be enrolled.

Eligibility

Primary outcome measure(s)

• Clinical efficacy — 14 days
  The main outcome is the clinical results of assessed by clinical physicians, where clinical outcomes are recorded as successful or unsuccessful, defined by the relief of clinical symptoms, which is defined as imaging improvement determined by the clinician, normalization or significant reduction of white blood cell counts and related inflammatory indicators including CRP, PCT, IL-6, etc.

Trial sites (1)

More The First Affiliated Hospital with Nanjing Medical University trials in China