GBM patients recevied traditional treatment options: GBM patients recevied traditional treatment options (including surgery combined with radiotherapy and chemotherapy)
Study summary
GBM patients receiving PDT treatment (50 cases，surgery combined with photodynamic therapy) and traditional treatment (50 cases，traditional surgery) in our hospital and partner hospitals were collected. The prognosis was analyzed by comparing with the control group from multiple perspectives such as image evaluation, imaging effect, Karnofsky score, median survival time and survival rate.
Eligibility
Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria:
Pathologically confirmed primary focal GBM; Recurrent GBM(single or satellite lesions); Multiple (multiple germinal centers)GBM.
Exclusion Criteria:
* Photosensitizer allergy.
* Severe coagulation disorder.
* Patients with severe cardiovascular and cerebrovascular diseases, especially patients in the acute stage.
* Multiple organ failure, end-stage patients. ⑤ Pregnant women: Photofrin is considered a class C pregnancy risk (toxic, non-teratogenic) drug with non-dialysis properties.
Non-gbm diagnosis: Patients with other types of brain tumors or diseases. 7 Do not agree to informed consent: patients who are unwilling to sign informed consent or do not agree to participate in the study.
Primary outcome measure(s)
Number of Participants with Treatment of Surgical combination Photodyanmic therapy — From June 2025 to June 2027
Trial sites (1)
Facility
City
Region
Status
Zhejiang Provincial People's Hospital
Hangzhou
Zhejiang
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This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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