The goal of this observational study is to develop and validate a predictive model for prolonged mechanical ventilation (PMV) following acute type A aortic dissection (ATAAD) surgery.
The main questions it aims to answer are:
1. To validate the predictive performance of the model for PMV after ATAAD surgery
2. To assess the proportion of PMV among patients undergoing ATAAD surgery
3. To evaluate the ICU length of stay and operative mortality in patients with PMV following ATAAD surgery
Eligibility
Sex
ALL
Min age
18 Years
Max age
18 Years
Healthy volunteers
No
Inclusion Criteria:
* Age ≥18 years;
* Diagnosis of acute type A aortic dissection (ATAAD) confirmed by computed tomography angiography and echocardiography;
* Patients who underwent aortic surgery requiring cardiopulmonary bypass (CPB), were admitted to the surgical intensive care unit (SICU), and received mechanical ventilation.
Exclusion Criteria:
* Reintubation;
* Intraoperative death or failure to survive beyond 72 hours postoperatively;
* Pregnancy;
* Severe comorbidities (e.g., lung cancer);
* Missing critical outcome data (e.g., short-term mortality, mechanical ventilation duration, reintubation).
Primary outcome measure(s)
The predictive performance of the model for prolonged mechanical ventilation (PMV) following acute type A aortic dissection (ATAAD) surgery — 72 hours after ATAAD surgery The predictive performance of PMV following ATAAD surgery includes its discriminative ability and calibration ablility.
The proportion of patients with PMV — 72 hours after ATAAD surgery The proportion of patients with PMV refers to the proportion of patients with PMV among the total included ATAAD postoperative patients. PMV is defined as postoperative mechanical ventilation lasting more than 72 hours
Trial sites (1)
Facility
City
Region
Status
Fuwai Hospital
Beijing
Beijing Municipality
More China-Japan Friendship Hospital trials in China
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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