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Clinical Trials in China / NCT06776835
Enrolling by invitation Observational

Screening of Small Non-coding RNAs as an Auxiliary Diagnostic Biomarker for Gastric Cancer

NCT06776835 · tracked via the Priya Life Science China tracker
Sponsor
Affiliated Hospital of Nantong University
Phase
Observational
Started
2023-12-10
Last updated
2025-01-15

Condition(s) studied

Stomach Neoplasms

Investigational drug(s) / intervention(s)

Analysis of relative quantitative of small non-coding RNAs

Analysis of relative quantitative of small non-coding RNAs: Each participant was enrolled to assess the of relative quantitative of small non-coding RNAs

Study summary

Gastric cancer is one of the most common malignancies of the gastrointestinal system, especially in East Asia. A host of patients are diagnosed with GC at the late stage, leading to poor patient prognosis. Therefore, there is a strong demand to develop new biomarkers to detect this tumor early. Small non-coding RNA species include microRNA (miRNA), PIWI-interacting RNA (piRNA), small interfering RNA (siRNA), tRNA-derived small RNA (tsRNA), etc. It has been demonstrated that small non-coding RNAs are involved in gastric cancer cell proliferation, metastasis, progression and survival. Hence, it is considered as an auxiliary diagnostic biomarker for gastric cancer.

Eligibility

Sex
ALL
Min age
18 Years
Max age
85 Years
Healthy volunteers
Accepted
Inclusion Criteria: * Having signed informed consent * Age≥ 18 years old and ≤ 85 years old * Histologically confirmed gastric cancer Exclusion Criteria: * Other previous malignancy within 5 year * Surgery (excluding diagnostic biopsy) within 4 weeks prior to study * Pregnancy or lactation period * Legal incapacity

Primary outcome measure(s)

  • Analysis of relative quantitative of small non-coding RNAs — an average of 2 years
    Relative quantitative of small non-coding RNAs are detected by quantitative RT-PCR

Trial sites (1)

FacilityCityRegionStatus
Affiliated Hospital of Nantong University Nantong Jiangsu

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06776835 on ClinicalTrials.gov ↗ ← All trials in China