Novel Serum Biomarkers for Identifying Plaque Erosion in ACS and Predicting Prognosis

Inclusion Criteria: people presenting with an acute coronary syndrome (ACS)-either non-ST-segment elevation myocardial infarction (NSTE-ACS); or ST-segment elevation myocardial infarction (STE-ACS), and subsequently underwent emergent coronary angiography followed by percutaneous coronary intervention (PCI). Culprit leisions were tested using optical coheren tomograpgy and pathological diagnosis(PE OR PR) were validated by 2 independent experienced core lab members. Exclusion Criteria: * patients younger than 18 years or older than 85 years * patients in cardiogenic shock * prior coronary artery bypass grafting, * patients with corornary stent thrombosis * patients with left main coronary disease * patients with congestive heart failure * patients with life-threatening arrhythmia * patients with thrombocytopenia patients with significant hepatic or renal impairment * patients with septicemia, leukopenia, active inflammatory or malignant disease * other factors compromising high-quality optical coherence tomography (OCT) imaging (e.g., severe vessel tortuosity or calcification, persistent no-reflow, lesions in distal segments, or an indeterminate culprit lesion) * Individuals unable to provide informed consent were also excluded.