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Clinical Trials in China / NCT06750783
Recruiting Phase 4

The Effects of Xuezhikang and Atorvastatin on Lipid in Patients With Dyslipidemia and Prediabetes

NCT06750783 · tracked via the Priya Life Science China tracker
Sponsor
Beijing Tsinghua Chang Gung Hospital
Phase
Phase 4
Started
2024-12-31
Last updated
2025-04-03

Condition(s) studied

Prediabetic State (IGT)

Investigational drug(s) / intervention(s)

XuezhikangAtorvastatin

Xuezhikang: The Xuezhikang group takes Xuezhikang at a dose of 600 milligrams twice a day, orally after meals;

Atorvastatin: The atorvastatin group takes atorvastatin 20mg once a day, orally after meals.

Study summary

This study compares the impact of Xuezhikang and atorvastatin on glucose metabolism to explore the incidence of prediabetes patients developing diabetes after 24 weeks of Xuezhikang use, and by investigating the effect of Xuezhikang on blood glucose fluctuations, discusses the possible mechanisms by which Xuezhikang affects glucose metabolism.

Eligibility

Sex
ALL
Min age
18 Years
Max age
Healthy volunteers
No
Inclusion Criteria: * Age ≥ 18 years old; * No gender restrictions; * Definition of pre diabetes: All subjects were tested with 75g OGTT to measure fasting and 2h venous serum glucose and glycosylated hemoglobin. Fasting blood glucose ≥ 6.1 and \< 7mmol/L, 2-hour serum glucose ≥ 7.8 and \< 11.1mmol/L after glucose load, and glycated hemoglobin\<6.5%; * Abnormal lipid metabolism: LDL-c ≥ 3.4 mmol/L and\<4.9 mmol/L, and TG ≤ 5.6 mmol/L; (2) Non-HDL-c ≥ 4.1mmol/L and\<5.7 mmol/L, and TG ≤ 5.6 mmol/L; * Voluntarily sign the informed consent form. Exclusion Criteria: * Patients who have met the diagnosis of diabetes; * Within 3 months prior to signing the informed consent form, there was an acute coronary syndrome, stroke, or transient ischemic attack. * ALT/AST\>3 times ULN; * Known myopathy, rhabdomyolysis, or creatine kinase levels greater than 4-fold ULN, and not caused by muscle injury; * Pregnant or planning to conceive; * Have used any lipid-lowering drugs within 3 months; * Individuals with allergies/contraindications to Xuezhikang and Atorvastatin. * Suffering from any of the following diseases: uncontrolled hyperthyroidism and hypothyroidism, severe heart failure, malignant tumors, hematopoietic system diseases, digestive system diseases affecting digestion and/or absorption function, mental disorders, other serious or unstable physical diseases. * History of alcohol or drug abuse or dependence within 3 months prior to joining the trial. * Participated in clinical trials of other drugs or devices within 3 months prior to joining the trial. * Researchers believe that other situations are not suitable for participating in the experiment.

Primary outcome measure(s)

Trial sites (3)

FacilityCityRegionStatus
Beiqijia Community Health Service Center, Changping District, Beijing Beijing Beijing Municipality Recruiting
Beijing Tsinghua Changgung Hospital Beijing Beijing Municipality Recruiting
Xiaotangshan Community Health Service Center, Changping District, Beijing Beijing Beijing Municipality Recruiting

On this site

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More Beijing Tsinghua Chang Gung Hospital trials in China

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06750783 on ClinicalTrials.gov ↗ ← All trials in China