Functional IOL Implantation in Patients With Epiretinal Membrane

NCT06719739 · tracked via the Priya Life Science China tracker

Sponsor

Eye & ENT Hospital of Fudan University

Phase

Not applicable

Started

2024-09-21

Last updated

2026-04-08

Condition(s) studied

CataractIntraocular Lens ComplicationEpiretinal Membrane

Investigational drug(s) / intervention(s)

Intraocular lens implantation

Intraocular lens implantation: Cataract patients scheduled for surgery will be evaluated by OCT, and those diagnosed with macular epiretinal membrane will be implanted in different IOLs according to the patients' decision: monodical IOL or functional IOL.

Study summary

We have designed this prospective study to evaluate macular involvement and epiretinal membrane (ERM) grading by OCT in eyes with ERM and to compare clinical outcomes after implantation of Enhance IOL with standard monofocal IOL in eyes with ERM grading preoperatively, aiming to find out whether functional IOL is benefit for patients with ERM.

Eligibility

Sex

ALL

Min age

20 Years

Max age

90 Years

Healthy volunteers

Inclusion Criteria: * Requirement for cataract extraction * Age \> 40 years * Axial length in 21mm to 25mm * ERM Exclusion Criteria: * Residual corneal astigmatism \> 1.0 D * Amblyopia * Previous ocular surgery * Other ocular pathologies apart from mERM, such as diabetic retinopathy, macular degeneration, glaucoma with field defects * Requirements for further ocular surgery (other than Nd:YAG capsulotomy) or retinal laser treatments during the study

Primary outcome measure(s)

UDVA — 1-day/1-week/1-month/3-months/6-monhts/1-year/2-years
Uncorrected distance visual acuity

Trial sites (2)

Facility	City	Region	Status
Eye and Ear, Nose, and Throat Hospital of Fudan University	Shanghai	Shanghai Municipality	Recruiting
Shanghai Heping Eye Hospital	Shanghai	Shanghai Municipality	Recruiting

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Other trials for the same condition

Multicenter Study on the Use of Intraoperative OCT in the Diagnosis and Management of Lens Diseases Active, not recruiting

Shanghai High Myopia Study Recruiting

Artificial Intelligence for Highly Myopic Cataract Recruiting

Anxiety in Cataract Patients Using Preoperative Music Therapy Active, not recruiting

Minimal Vitrectomy Surgery for Epiretinal Membrane Recruiting

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06719739 on ClinicalTrials.gov ↗ ← All trials in China