Study of Acupuncture to Control Weight and Improve Pregnancy Rates in Overweight/Obese PCOS Patients

Inclusion Criteria: 1. Diagnosis of PCOS according to the 2003 Rotterdam criteria with at least two of the following three symptoms: clinical and/or biochemical signs of hyperandrogenism (hirsutism or acne), oligomerism/amenorrhea, and/or polycystic ovaries (PCOS). Biochemical hyperandrogenism is defined as total testosterone \> 2.6 nmol/L or free androgen index \>7. Hirsutism is defined as an FG score ≥7. Oligomenorrhea is defined as menstrual bleeding \> 35 days between menstrual periods in the past year, \< 8 menstrual bleeding. Amenorrhea is \< 3 cycles per year. PCO is defined by transvaginal ultrasound, where one or both ovaries ≥ 12 follicles 2-9 mm and/or ovarian volume ≥ 10 mL. Other endocrine disorders such as atypical congenital adrenal hyperplasia (17-hydroxyprogesterone \<3 nmol/L), androgen-secreting tumors, or suspected Cushing syndrome are excluded. 2. Age from ≥ 20 years old (legal age of marriage) to ≤ 40 years old 3. PCOS patients: BMI ≥ 25 to ≤40kg/m2. 4. Willing to sign the consent form. Exclusion Criteria: 1. History of severe heart disease, hematologic disease; 2. Known kidney disease (creatinine clearance rate \<45mL/min), liver function ALT, AST more than 3 times the normal value, autoimmune disease or cancer; 3. Any acute disease that has the potential to alter renal function or cause tissue hypoxia; 4. Type I diabetes mellitus; 5. Medication within 12 weeks (hormonal drugs, antidepressants, other anti-diabetic drugs, contraceptives, ovulation induction drugs or other drugs that affect the trial in the judgment of the investigator); 6. Allergy to metformin hydrochloride or any excipients; 7. Blood pressure \> 160/100 mm Hg; 8. Pregnancy or breastfeeding in the past three months; 9. No history of acupuncture treatment within 2 months; 10. Alcohol dependence 11. Persons with disabilities with language impairment or reduced ability to understand the information provided; 12. Those who have participated in other clinical studies within three months; 13. The man clearly diagnoses infertility-related diseases and factors.