Nomogram for Predicting Difficult Transoral and Submental Thyroidectomy

Condition(s) studied

Investigational drug(s) / intervention(s)

Observations on clinicopathological factors influencing the difficulty of surgery: Age, body mass index, gender, thyroid function parameters, lesion size, lesion location, ultrasound data

Study summary

No prior studies have stratified the difficulty of transoral and submental thyroidectomy (TOaST). The investigators aimed to investigate preoperative factors as indicators of difficult TOaSTs and to develop a predictive model accordingly.

Eligibility

Primary outcome measure(s)

• Number of participants with recurrent laryngeal nerve injury — through study completion, an average of 1 year
  impaired vocal cord mobility confirmed by postoperative laryngoscopy
• Number of participants with hypoparathyroidism — through study completion, an average of 1 year
  a postoperative parathyroid hormone level of less than 10 pg/ml
• Number of participants with mental nerve injury — through study completion, an average of 1 year
  a postoperative numbness in the lower lip and submental area
• operative time — through study completion, an average of 1 year
  operative time was defined as the duration from incision to closure, and was collected from anesthesia record sheet

Trial sites (1)

More Shanghai 6th People's Hospital trials in China