Temporal Interference: Researchers applied temporal interference (TI) stimulation to the deep brain nuclei of patients who had undergone SEEG monitoring, recording changes in electrical activity detected by SEEG.
Study summary
This single-center prospective study aims to investigate the electrophysiological mechanisms of temporal interference (TI) in humans by analyzing clinical, imaging, and electrophysiological data from patients aged 14-60 with drug-resistant epilepsy.
Eligibility
Sex
ALL
Min age
14 Years
Max age
65 Years
Healthy volunteers
No
Inclusion Criteria:
* Clinical diagnosis of drug-resistant epilepsy;
* No severe systemic diseases;
* Implantation of stereotactic electrodes;
* Agreement to participate in this study and signs the informed consent form.
Exclusion Criteria:
* Hematoma at the scalp electrode site or fluid accumulation under the electrode after intracranial electrode placement.
Primary outcome measure(s)
Electrophysiological changes — During the trial(up to 3 hours for each subject) Electrophysiological waveform changes recorded by stereoelectroencephalography (SEEG) before, during, and after TI stimulation.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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