This study does not involve any interventions: This study does not involve any interventions
Study summary
To investigate the influence of Neuromediators expression in corneal stromal lenticules and corneal injury repair after small incision extraction
Eligibility
Sex
ALL
Min age
18 Years
Max age
45 Years
Healthy volunteers
Accepted
Inclusion Criteria:
* age ≥ 18 years with stable refraction for at least two years;
* spherical equivalent (SE) \< -6.00 D;
* corrected distance visual acuity of 20/20 or better;
* no history of using rigid gas permeable lenses or orthokeratology (OK) lenses prior to examination
Exclusion Criteria:
\- a history of moderate to severe dry eye as well as any ocular or systemic disease that would contraindicate laser refractive surgery.
Primary outcome measure(s)
Corneal stromal lenticule Neuromediators — baseline Corneal neuromediators, including NGF(pg/mL), CGRP(pg/mL), SP(pg/mL), IGFBP-1(ng/mL), and MANF(pg/mL), which play pivotal roles in maintaining normal physiological functions of the cornea.
Trial sites (1)
Facility
City
Region
Status
Shanghai Tenth People's Hospital
Shanghai
Shanghai Municipality
Recruiting
Official registry record
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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